Illumina

Illumina

Enterprise AI Architect

US - California - San Diego, USA · Senior

H1B sponsorship available$156k-$233kDetected 92 days ago
CI/CDLLMsRAGAgentic AIA/B TestingLeadershipCollaboration

About the role

  • At Illumina, we are applying AI to meaningful problems that can improve human health at global scale.
  • This role is ideal for a hands-on AI leader who combines strong technical judgment with a builder mindset, learns quickly in a fast-moving space, and can influence direction in a complex enterprise environment.

Responsibilities

  • Collaborate & Innovate: Partner with business, product, engineering, and architecture teams to identify high-value opportunities, define practical use cases, and co-create GenAI and agentic AI solutions that solve real enterprise needs.
  • Advise & Align: Partner with senior stakeholders to connect AI opportunities to business priorities, guide decision-making with sound technical judgment, and ensure solutions are designed for both near-term value and long-term scalability.
  • Architect End-to-End: Design and communicate scalable AI-enabled applications, services, and workflows, using Illumina's existing technology stack while identifying where new capabilities can accelerate impact.
  • Train & Elevate: Document your playbooks, prompts, and patterns in our internal knowledge base, helping the whole organization move faster.
  • Influence & Elevate: Document playbooks, prompts, patterns, and lessons learned to help teams adopt best practices, move faster, and build more consistently across the enterprise.
  • Typically requires 8+ years of relevant experience in software, architecture, AI, or solution design, with a track record of delivering scalable solutions in production environments.
  • As our Lead AI Solutions Architect, you will design, prototype, and help scale AI solutions that drive measurable business impact across the enterprise.
  • You will partner closely with business, product, engineering, and architecture leaders to translate high-value opportunities into practical GenAI and agentic AI solutions.

Requirements

  • recent hands on experience designing and delivering production-grade applications, services, or workflows, with the ability to translate business needs into scalable technical solutions.
  • Experience with modern application development across frontend, backend, APIs, or microservices is highly valued.
  • Hands-on experience with modern AI technologies such as LLM-based applications, RAG, prompt design, agentic workflows, vector search, model orchestration, or multimodal AI.
  • You know how to turn emerging capabilities into practical, usable solutions.
  • Applied Architecture Depth: recent hands on experience designing and delivering production-grade applications, services, or workflows, with the ability to translate business needs into scalable technical solutions.
  • GenAI & Agentic AI Experience: Hands-on experience with modern AI technologies such as LLM-based applications, RAG, prompt design, agentic workflows, vector search, model orchestration, or multimodal AI.
  • Typically requires a minimum of 15 years of related experience with a Bachelor's degree; or 12 years and a Master's degree, or equivalent experience.

Compensation

  • The estimated base salary range for the Enterprise AI Architect role based in the United States of America is: $155,600 - $233,400.

Benefits

  • At Illumina, we are expanding access to genomic technology to realize health equity for billions of people around the world.
  • Our efforts enable life-changing discoveries that are transforming human health through the early detection and diagnosis of diseases and new treatment options for patients.
  • Lead with Vision: shape Illumina's approach to GenAI and agentic AI by translating emerging capabilities into clear architectural direction, scalable patterns, and practical guidance for teams across the enterprise.

Company info

  • You translate complex AI concepts for both architects and executives and guide customers through technical decisions aligned to business objectives.
  • Prototype Rapidly: Apply an AI-first experimentation mindset-build proof points in days, iterate on feedback, and drive quick wins for our internal and external customers.
  • Working at Illumina means being part of something bigger than yourself.
  • Every person, in every role, has the opportunity to make a difference.

Visa & Work Authorization

  • This role is not eligible for visa sponsorship.
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This listing is sourced directly from Illumina's careers page and normalized into a canonical job model.