Illumina
Enterprise AI Architect
US - California - San Diego, USA · Senior
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odds of building a lasting career here
Sponsors, but it's cap-subject — you still face the weighted lottery (~61% per draw at Level IV). Good if you win; have a cap-exempt backup on your list.
Lottery odds assume a STEM candidate.
Personalize to your clock →H-1B wage level
the lottery is wage-weighted — each level is one more entry
$27,190 more — $182,790 — moves this role to Level IV and 4 lottery entries. That figure is inside the range the employer already advertised.
Based on the DOL prevailing wage for this occupation and worksite, a base salary of $182,790 would place this position at wage Level IV. That figure is within the posted range, and I'd like to target it. This role classifies under "Software Developers" for prevailing-wage purposes.
DOL prevailing wage, 2026-27 wage year · Software Developers (15-1252) · Bakersfield-Delano, CA. Wage level is derived by USCIS from the offered wage, occupation and worksite; the occupation shown is inferred from the job title.
Employer immigration record
from this employer's Department of Labor filings
Green-card filing pattern in this occupation
Green-card follow-through: 100%
Files H-1B transfers
Sourced from Department of Labor LCA, PERM and prevailing-wage disclosure data. Employer matching is by name, so figures may be split across an employer's legal entities. Absence of a filing means none appears in our copy of the data, not that none exists.
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About the role
- At Illumina, we are applying AI to meaningful problems that can improve human health at global scale.
- This role is ideal for a hands-on AI leader who combines strong technical judgment with a builder mindset, learns quickly in a fast-moving space, and can influence direction in a complex enterprise environment.
Responsibilities
- Collaborate & Innovate: Partner with business, product, engineering, and architecture teams to identify high-value opportunities, define practical use cases, and co-create GenAI and agentic AI solutions that solve real enterprise needs.
- Advise & Align: Partner with senior stakeholders to connect AI opportunities to business priorities, guide decision-making with sound technical judgment, and ensure solutions are designed for both near-term value and long-term scalability.
- Architect End-to-End: Design and communicate scalable AI-enabled applications, services, and workflows, using Illumina's existing technology stack while identifying where new capabilities can accelerate impact.
- Train & Elevate: Document your playbooks, prompts, and patterns in our internal knowledge base, helping the whole organization move faster.
- Influence & Elevate: Document playbooks, prompts, patterns, and lessons learned to help teams adopt best practices, move faster, and build more consistently across the enterprise.
- Typically requires 8+ years of relevant experience in software, architecture, AI, or solution design, with a track record of delivering scalable solutions in production environments.
- As our Lead AI Solutions Architect, you will design, prototype, and help scale AI solutions that drive measurable business impact across the enterprise.
- You will partner closely with business, product, engineering, and architecture leaders to translate high-value opportunities into practical GenAI and agentic AI solutions.
- You will help shape scalable patterns, accelerate adoption, and ensure the solutions we build are both innovative and enterprise-ready.
Requirements
- Typically requires a minimum of 15 years of related experience with a Bachelor's degree
- or 12 years and a Master's degree, or equivalent experience.
- Applied Architecture Depth: recent hands on experience designing and delivering production-grade applications, services, or workflows, with the ability to translate business needs into scalable technical solutions.
- Experience with modern application development across frontend, backend, APIs, or microservices is highly valued.
- GenAI & Agentic AI Experience: Hands-on experience with modern AI technologies such as LLM-based applications, RAG, prompt design, agentic workflows, vector search, model orchestration, or multimodal AI.
- You know how to turn emerging capabilities into practical, usable solutions.
- Typically requires a minimum of 15 years of related experience with a Bachelor's degree; or 12 years and a Master's degree, or equivalent experience.
Compensation
- The estimated base salary range for the Enterprise AI Architect role based in the United States of America is: $155,600 - $233,400.
Benefits
- At Illumina, we are expanding access to genomic technology to realize health equity for billions of people around the world.
- Our efforts enable life-changing discoveries that are transforming human health through the early detection and diagnosis of diseases and new treatment options for patients.
Company info
- Working at Illumina means being part of something bigger than yourself.
- Position Summary At Illumina, we are applying AI to meaningful problems that can improve human health at global scale.
- Prototype Rapidly: Apply an AI-first experimentation mindset-build proof points in days, iterate on feedback, and drive quick wins for our internal and external customers.
- Every person, in every role, has the opportunity to make a difference.
Visa & Work Authorization
- This role is not eligible for visa sponsorship.
This listing is sourced directly from Illumina's careers page and normalized into a canonical job model.