AstraZeneca

AstraZeneca

Senior Scientist, Allogeneic T-Cell Therapy Process Development

US - Gaithersburg - MD · Senior

Sponsorship not specified$112k-$168kDetected 3 days ago
SwiftData AnalysisProcess ImprovementGMPCRISPRFlow CytometryNGSCell CultureExperimental DesignProtein AnalysisCommunicationCollaborationProblem SolvingMentoringWriting

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odds of building a lasting career here

59Sponsors, lottery-bound
Cap-exempt (no lottery)0
Sponsors this role100
Entry-level history0
PERM / green-card track0
Lottery odds (Level III)83
Fits your clock70

Sponsors, but it's cap-subject — you still face the weighted lottery (~45% per draw at Level III). Good if you win; have a cap-exempt backup on your list.

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About the role

  • Senior Scientist, Allogeneic T-Cell Therapy Process Development: Cell Therapy CMC Do you have a passion for science?
  • Would you like to apply your expertise to impact a company that follows the science and turns ideas into life changing medicines?
  • Then AstraZeneca might be the one for you!

Responsibilities

  • The role will require performing gene editing activities and manipulation of human primary cells, while applying strong scientific judgment to support process optimization, process characterization, and development of scalable manufacturing approaches.
  • As a Senior Scientist, you will independently own the design, execution, analysis, interpretation, and documentation of process development studies.
  • You will be expected to lead studies with minimal supervision, use data-driven decision-making to guide next steps, troubleshoot technical challenges, and contribute to the overall technical strategy for allogeneic CAR-T and TCR-T process development.
  • Strong background in experimental design and data analysis skills are essential.
  • 29-Sep-2026 Our mission is to build an inclusive environment where equal employment opportunities are available to all applicants and employees.
  • Our Gaithersburg, Maryland facility creates life-changing medicines for people around the world.
  • This campus employs more than 3,500 experts in our field and is only a short drive from Washington, DC.
  • Here, we play host to some of the most cutting-edge technology and lab spaces, all designed to inspire collaboration and cross-functional science.
  • This is where you'll find newly designed, activity-based workspaces to suit a variety of working styles while increasing collaboration between teams.

Requirements

  • Experience culturing human primary cell s (T cell culture experience necessary ).
  • Experience engineering cell s in scale - up processes with manufactur e-ready genome editing tools and DNA / RNA transfection approaches.
  • Ability to think critically, analytically and have demonstrated troubleshooting and problem-solving skills based on deductive reasoning.
  • Excellent teamwork and communication skills including proven technical writing skills are required.
  • Experience with cell editing technologies: CRISPR/Cas9, base editing, etc.

Skills

  • Knowledge abou t immunology is highly desirable.
  • Experience with viral transduction techniques desirable.
  • GMP experience preferred.
  • Experience with cell characterization ( dPCR, ELISA, NGS) ideal.
  • Experience with cell editing
  • CRISPR/Cas9, base editing, etc.
  • Education /Experience:
  • Why AstraZeneca?
  • Delivering life-changing medicines is about being entrepreneurial - finding those moments and recognizing their potential.
  • Come and join our journey.
  • So, what's next!
  • The annual base pay for this position ranges from $112,304.00 - $168,456.00.

Compensation

  • The annual base pay for this position ranges from $112,304.00 - $168,456.00.

Benefits

  • offered include qualified retirement programs, paid time off (i.e., vacation, holiday, and leaves), as well as health, dental, and vision coverage in accordance with the terms of the applicable plans.
  • We believe employees benefit from being challenged and inspired at work.
  • This includes a fitness center, employee healthcare clinic, electric vehicle charging stations, dry cleaning, full-service cafeteria and copy center.

Company info

  • We are looking for a Senior Scientist to join our Allogeneic T-Cell Therapy Process Development team.
  • At AstraZeneca, we put patients first and strive to meet their unmet needs worldwide.
  • We are dedicated to creating a culture of inclusion and collaboration.

Equal opportunity

  • If you have a disability or special need that requires accommodation, please complete the corresponding section in the application form.
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This listing is sourced directly from AstraZeneca's careers page and normalized into a canonical job model.