Vir Biotechnology
Scientist I, Analytical Development - Protein Chemistry (Temporary)
San Francisco, California, United States · Junior · Contract
Sponsorship not specifiedDetected 37 days ago
Data AnalysisIntellectual PropertyExperimental DesignMass SpectrometryAnimal StudiesCollaboration
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Lottery odds40
Fits your clock70
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About the role
- The successful candidate will be responsible for supporting the operation of analytical development labs, including a mass spectrometry facility, and be a key member on project teams.
- This role is located in our San Francisco headquarters with an expectation of at least 4 days per week in office.
Responsibilities
- Hands-on analytical lab support for process development, formulation development, analytical methods development, and product characterization for projects at various clinical stages
- Perform all relevant analytical testing and report results in collaboration with the process development and drug product teams
- Apply mass spectrometry techniques and other analytical methods to support characterization of Vir products
- Perform forced degradation, comparability, structure-activity relationship studies to evaluate Vir products (e.g., for aggregation, charge variants, post-translational modifications, etc.), and perform CQA assessments
- Manage method development and characterization testing at external partners by providing technical review of protocols, reports, data analysis, and troubleshooting method-related issues
- Ability to investigate observations in analytical data through experimental design, historical data trending, and literature review.
- Vir Biotechnology, Inc. is a clinical-stage biopharmaceutical company focused on powering the immune system to transform lives by discovering and developing medicines for serious infectious diseases and cancer.
Requirements
- Technical expertise and hands-on experience in characterization of biologics and associated impurities with U/HPLC, CE-SDS, and iCIEF assays.
- Ability to collect, process, interpret, and present analytical data independently.
- Experience with method transfer and method qualification/validation at CROs
- Ability to trouble-shoot method-related issues at CMOs and CROs
Nice to have
- Knowledge and hands-on experience in state-of-the-art protein mass spectrometry techniques (instrumentation and data analysis software).
- Previous experience on oligonucleotide mass spectrometry analysis is a plus
- Knowledge and experience on comparability study, CQA assessment, and forced degradation study is a plus. <span data-ccp-props="{"201341983":0,"335559739":1
Company info
- We are committed to creating a company where everyone feels supported and encouraged to give their best.
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