Alta Resource Technologies, Inc.
Scientist I, Computation Protein Design
Boulder, CO
No sponsorship$140k-$175kDetected 13 days ago
PythonAWSGCPAzureDockerMachine LearningTensorFlowPyTorchSparkData EngineeringStatisticsSupply ChainBioinformaticsLeadershipCommunicationCollaborationMentoring
About the role
- This role focuses on leveraging and optimizing foundational AI models to accelerate our protein engineering pipeline.
Responsibilities
- Develop and implement rigorous evaluation frameworks to assess model performance, including metrics for protein structure prediction, sequence optimization, and functional property prediction
- Design and execute computational experiments to validate model predictions against experimental data
- Leverage multiple information sources (including bioinformatic, structural, simulations, and experimental performance data) to improve internal models and develop agentic frameworks
- Collaborate with the Applied Biology team to translate models into actionable insights.
- Create technical documentation including model assumptions, equations, validation results, and recommendations.
- Contribute to developing data management systems that meet FAIR principles.
- Develop analysis code to support the team in analyzing experimental data.
- The opportunity to lead a breakthrough program redefining U.S. supply chain resilience in critical materials.
- We believe that varied perspectives, experiences, and backgrounds strengthen our team and drive better outcomes for our clients and partners.
Requirements
- Ph.D. in Computational Biology, Bioinformatics, Computer Science with 1-3 years of relevant industry or post-doctoral experience, or M.S. with 6+ years of relevant industry experience
- Hands-on experience with protein foundation models such as ESM-2, ESM-3, ProteinMPNN, RFdiffusion, AlphaFold, or similar architectures
- Strong proficiency in Python and modern ML frameworks (PyTorch, TensorFlow, JAX)
- Experience with model evaluation methodologies, including cross-validation, performance metrics, and statistical analysis
- Experience with high-performance computing environments and GPU-accelerated computing
- Strong communication skills and ability to work collaboratively in interdisciplinary teams
- US Citizenship required.
Nice to have
- Experience with workflow management tools (Nextflow, Snakemake, or similar)
- Familiarity with cloud computing platforms (AWS, GCP, Azure) and containerization (Docker, Singularity)
- Experience with distributed computing frameworks (Dask, Ray, Spark)
- Preferred, But Not Required:
Skills
- This mineral challenge represents a historic opportunity for technology development and value creation.
- Alta is proud to be at the vanguard of this mega trend.
Compensation
- Competitive compensation and benefits package.
Benefits
- Competitive compensation and benefits package.
- The starting pay range for this position is $140,000 to $175,000 commensurate with educational background and work experience.
- Benefits including, 401(K) medical, dental, and vision plans, or equivalent, will be provided.
- Paid parental leave, paid sick leave, flexible time off, company holidays.
Equal opportunity
- equal opportunity employer committed to building a workforce that reflects the diversity of the communities we serve.
Visa & Work Authorization
- US Citizenship required
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