Personalis, Inc

Personalis, Inc

Product Development - Research Associate 2 / Sr. Research Associate

Fremont, CA · Senior · Full-time

Sponsorship not specified$85k-$115kDetected 56 days ago
AlgorithmsBioinformaticsMolecular BiologyNGSResearchCommunicationCollaboration

Stay score

odds of building a lasting career here

47Sponsors, lottery-bound
Cap-exempt (no lottery)0
Sponsors this role80
Entry-level history0
PERM / green-card track0
Lottery odds (Level II)66
Fits your clock70

Sponsors, but it's cap-subject — you still face the weighted lottery (~30% per draw at Level II). Good if you win; have a cap-exempt backup on your list.

Lottery odds assume a STEM candidate.

Personalize to your clock →

H-1B wage level

the lottery is wage-weighted — each level is one more entry

Level I · 1×
Level I$114,8991 entry
Level II$141,6482 entries
Level III$168,3763 entries
Level IV$195,1254 entries

The bottom of this range ($85,000) is below the Level I prevailing wage of $114,899. An H-1B cannot be filed below the prevailing wage, so an offer at the floor of this band could not be sponsored as posted.

DOL prevailing wage, 2026-27 wage year · Biochemists and Biophysicists (19-1021) · San Francisco-Oakland-Fremont, CA. Wage level is derived by USCIS from the offered wage, occupation and worksite; the occupation shown is inferred from the job title.

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About the role

  • Personalis is based in Fremont, California.
  • The base pay actually offered will take into account internal equity and also may vary depending on the candidate's geographic region, job-related knowledge, skills, and experience among other factors.

Responsibilities

  • Assay & Workflow Execution: Support R&D scientists in developing, optimizing, and validating novel oncology assays and workflows.
  • Protocol Refinement: Evaluate new protocols as a front-line user and provide constructive feedback to optimize standard operating procedures (SOPs).
  • Documentation & Reporting: Maintain meticulous sample tracking and experimental records in lab notebooks
  • Compliance: Maintain compliance with safety guidelines, quality standards, and company policies.
  • Documentation & Reporting: Maintain meticulous sample tracking and experimental records in lab notebooks; present findings in team meetings.
  • We aim to drive a new paradigm for cancer management, guiding care from biopsy through the life of the patient.
  • Our highly sensitive assays combine tumor-and-normal profiling with proprietary algorithms to deliver advanced insights even as cancer evolves over time.
  • Our products are designed to detect minimal residual disease (MRD) and recurrence at the earliest timepoints, enable selection of targeted therapies based on ultra-comprehensive genomic profiling, and enhance biomarker strategy for drug development.
  • In this role, you will collaborate with a multidisciplinary R&D team of scientists, assay developers, and clinicians to plan, execute, and analyze cutting-edge oncology solutions.
  • You will provide hands-on NGS equipment operation and library preparation using real-world samples to develop novel precision medicine products used by pharma, biotech, and clinical partners.

Requirements

  • Technical Expertise: Proficiency in DNA/RNA extraction, quality control (e.g., Qubit, TapeStation), and NGS library preparation.
  • Education: BS/MS in Molecular Biology, Genomics, Biochemistry, or a related biological science.
  • Skills & Drive: Strong organizational and communication skills with a drive to learn in a fast-paced, hands-on environment
  • The hiring range for this position is $85,000 to $115,000 per year, which may factor in various geographic regions. The base pay actually offered will take into account internal equity and also may vary depending on the candidate's geographic region, job-related knowledge, skills, and experience among other factors. Our full-time regular positions also include an annual performance-based bonus (or a sales incentive plan) and long-term incentive units (equity) provided as part of our compensation package, in addition to a full range of medical, financial, and/or other benefits, dependent on the level and position offered.
  • Personalis is an equal opportunity employer and is committed to the full inclusion of all individuals. As part of this commitment, Personalis will ensure that persons with disabilities are provided with reasonable accommodations. If you need an accommodation to participate in the job application or interview process, to perform essential job functions, and/or to receive other benefits and privileges of employment, please let your recruiter know, if/when they contacts you.
  • Protecting Our Candidates: At Personalis, we value your security. Please note that all official correspondence from our team will come exclusively from @ personalis.com email addresses. We will never ask for personal financial information or conduct interviews over text or chat platforms. If you receive a suspicious request, it is likely a scam. We are committed to a safe recruitment experience and actively work with authorities to investigate and prosecute cyber crimes targeting our community.
  • Personalis is an Equal Opportunity Employer/Minorities/Females/Veterans/Disabilities. Personalis offers a competitive compensation package and benefits including medical, dental, vision, 401(k) match, ESPP, tuition reimbursement, sick/vacation time, commuter benefits/ EV charging stations, onsite gym, and wellness benefits. (For US only, benefits in other countries may vary.)

Nice to have

  • 3+ years of hands-on molecular biology laboratory experience (biotech/pharma preferred).
  • Technical Expertise:
  • Proficiency in DNA/RNA extraction, quality control (e.g., Qubit, TapeStation), and NGS library preparation.
  • Assay Specialization:
  • Experience with liquid biopsy (cfDNA/cfRNA) or FFPE sample processing is strongly preferred.
  • Assay Specialization: Experience with liquid biopsy (cfDNA/cfRNA) or FFPE sample processing is strongly preferred.

Skills

  • The hiring range for this position is $85,000 to $115,000 per year, which may factor in various geographic regions.
  • Personalis is an equal opportunity employer and is committed to the full inclusion of all individuals.
  • Protecting Our Candidates:
  • Personalis is an Equal Opportunity Employer/Minorities/Females/Veterans/Disabilities.
  • #LI-KK1 #LI-Hybrid

Compensation

  • The hiring range for this position is $85,000 to $115,000 per year, which may factor in various geographic regions.

Company info

  • At Personalis, we are transforming the active management of cancer through breakthrough personalized testing.
  • As part of this commitment, Personalis will ensure that persons with disabilities are provided with reasonable accommodations.
  • Protecting Our Candidates: At Personalis, we value your security.
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This listing is sourced directly from Personalis, Inc's careers page and normalized into a canonical job model.