Parabilis Medicines
Associate Director, Pharmacology
Cambridge, MA · Director
Sponsorship not specified$165k-$200kDetected 40 days ago
Node.jsPharmacologyExperimental DesignAnimal StudiesLeadershipCommunication
About the role
- The company has pioneered a new class of alpha-helical peptides - Helicons™ - capable of modulating intracellular proteins that have historically been beyond the reach of conventional medicines.
- Zolucatetide is being evaluated in the clinic across multiple Wnt/β-catenin-driven diseases, including desmoid tumors, familial adenomatous polyposis (FAP) and a range of other solid tumor indications.
- Beyond zolucatetide, Parabilis is advancing additional Helicon-based programs focused on other challenging targets where we believe our medicines could have life-altering impact.
Requirements
- PhD. in Pharmacology, Biology, or related field with 8+ years post-degree experience with a minimum of 2+ years of program leadership and people management experience
- Experience supporting first-in-class or novel mechanism oncology programs
- Experience working with small molecules, peptides, degraders (e.g., PROTACs), or biologics
- experience contributing to an IND submission required
- Strong expertise in in vivo pharmacology, PK/PD modeling concepts, and mechanistic biomarker strategy
- Enthusiastic and innovative mindset with the ability to thrive in a dynamic, fast-pasted, and highly collaborative environment
Nice to have
- Demonstrated ability to utilize AI tools for day-to-day work
- baseline proficiency is expected, and advanced or innovated use of AI is a strong plus
Skills
- Integrate pharmacology data with DMPK, safety, and biomarker findings to inform development decisions
- Clearly present data and strategy updates to senior leadership and governance teams
- Inspire and mentor junior pharmacology team members
Compensation
- The base salary target for this position is $165,000 - $200,000 per year, depending on experience, qualifications, and internal practices.
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