Vir Biotechnology

Vir Biotechnology

Senior Director, Clinical Research-Program Executive-Oncology

San Francisco, California, United States · Director · Full-time

No sponsorship$236k-$330kDetected 23 days ago
NegotiationHRIntellectual PropertyClinical TrialsClinical ResearchPharmacologyFDA RegulatoryResearchAnimal StudiesLeadershipCommunicationPublic SpeakingRegulatory Affairs

Stay score

odds of building a lasting career here

59Sponsors, lottery-bound
Cap-exempt (no lottery)0
Sponsors this role80
Entry-level history0
PERM / green-card track0
Lottery odds (Level IV)94
Fits your clock70

Sponsors, but it's cap-subject — you still face the weighted lottery (~61% per draw at Level IV). Good if you win; have a cap-exempt backup on your list.

Lottery odds assume a STEM candidate.

Personalize to your clock →

H-1B wage level

the lottery is wage-weighted — each level is one more entry

Level II · 2×
Level I$167,6481 entry
Level II$208,5822 entries
Level III$249,5383 entries
Level IV$290,4724 entries

$14,038 more — $249,538 — moves this role to Level III and 3 lottery entries. That figure is inside the range the employer already advertised.

Based on the DOL prevailing wage for this occupation and worksite, a base salary of $249,538 would place this position at wage Level III. That figure is within the posted range, and I'd like to target it. This role classifies under "Natural Sciences Managers" for prevailing-wage purposes.

DOL prevailing wage, 2026-27 wage year · Natural Sciences Managers (11-9121) · San Francisco-Oakland-Fremont, CA. Wage level is derived by USCIS from the offered wage, occupation and worksite; the occupation shown is inferred from the job title.

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About the role

  • Vir Biotechnology is seeking an experienced Senior Director, Clinical Research Oncology Program Executive (PE) to serve as the development team leader and single point of accountability for one or more oncology development programs.
  • This highly visible leadership role sits at the intersection of clinical development, program strategy, and corporate execution.
  • The Oncology PE will be responsible for defining and driving the overall development strategy, ensuring alignment across functions, and leading cross-functional teams to achieve key development milestones.

Responsibilities

  • Lead cross-functional program teams to align on objectives, priorities, timelines, resource needs, and risk mitigation strategies
  • Partner with executive leadership and governance committees to support strategic decision-making and portfolio prioritization
  • Mentor and develop team members while helping strengthen program leadership capabilities across the organization
  • Own the integrated development plan and target product profile, including stage gates, evidence requirements, and clear go/no-go recommendations.
  • Maintain integrated financial, timeline, resource, dependency, and risk scenarios; recommend corrective action as assumptions or data change.
  • Engage investigators, key opinion leaders, collaborators, and potential partners, incorporating external insights into program strategy.

Requirements

  • 15+ years of biotechnology or pharmaceutical industry experience with substantial experience in oncology drug development
  • Deep understanding of oncology clinical development, including experience across early and late-stage development
  • Strong strategic thinking and ability to integrate scientific, clinical, regulatory, operational, and commercial considerations into development plans
  • Experience presenting to executive leadership teams, governance committees, boards, and external stakeholders
  • Track record of advancing an oncology program through a major value inflection point, such as first-in-human entry, proof of concept, dose selection, pivotal initiation, regulatory submission, or approval.
  • Ability to make decisions under uncertainty and communicate the rationale, assumptions, alternatives, and consequences clearly.
  • Ability to travel domestically and internationally as needed.

Nice to have

  • board certification in Oncology, Hematology/Oncology, or a related specialty preferred

Compensation

  • The expected salary range for this position is $235,500 to $329,500 per year.

Benefits

  • Define and drive overall program vision, clinical development strategy, key milestones, and integrated development plans
  • Define data-readout and evidence-generation plans that support rapid learning, early de-risking, and disciplined investment.
  • Partner with Regulatory Affairs on global strategy, health-authority engagement, dose optimization, and expedited-development opportunities supported by data.
  • Coordinate Clinical Operations, Biometrics, Safety, CMC/Technical Operations, Medical Affairs, and Commercial to ensure integrated execution, inspection readiness, and a coherent program narrative.
  • Experience serving as a Medical Director, Clinical Research Physician, Program

Company info

  • The expected salary range for this position is $235,500 to $329,500 per year.
  • Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors.
  • Vir Biotechnology's compensation and benefits are aligned with the current market and commensurate with the person's experience and qualifications.
  • All full-time employees receive a package that includes compensation, bonus and equity as well as many other Vir Biotechnology benefits and perks such as health and welfare benefit plans, non-accrual paid time off, company shut down for holidays, commuter benefits, 401K match and lunch each day in the office.
  • Applicants must currently be authorized to work for any employer in the U.S. We are unable to sponsor or take over sponsorship of an employment Visa at this time.
  • All employment decisions at Vir Biotechnology are based on legitimate, non-discriminatory business requirements, job duties and individual qualifications.
  • Employment decisions are made without regard to any legally protected characteristics.
  • This commitment extends to all management practices and decisions, including recruitment and hiring, compensation, appraisal systems, promotions, training and career development programs.
  • Vir Biotechnology also strongly commits to providing employees with a work environment free of unlawful conduct or harassment.
  • Vir Biotechnology Human Resources leads recruitment and employment for Vir Biotechnology.
  • Unsolicited resumes sent to the company from recruiters do not constitute any type of relationship between the recruiter and Vir Biotechnology and do not obligate us to pay fees should we hire from those resumes.
  • We ask that external recruiters and/or agencies not contact or present candidates directly to our hiring manager or employees.
  • For hires based in the United States, Vir Biotechnology, participates in E-Verify.

Visa & Work Authorization

  • Applicants must currently be authorized to work for any employer in the U.S. We are unable to sponsor or take over sponsorship of an employment Visa at this time.

This listing is sourced directly from Vir Biotechnology's careers page and normalized into a canonical job model.