Stylus Medicine

Stylus Medicine

Principal Scientist, Computational Biology

Cambridge, Massachusetts, United States · Principal

Sponsorship not specified$180k-$195kDetected 131 days ago
PythonPandasNumPyData AnalysisData ScienceStatisticsIntellectual PropertyBioinformaticsNGSLab ResearchExperimental DesignAnimal StudiesCommunicationCritical Thinking

About the role

  • Contribute to patent filings, regulatory submissions, and scientific publications

Responsibilities

  • Build integrated workflows to annotate and characterize target sites by synthesizing proprietary datasets with large-scale public genomic databases
  • Design, implement, and scale robust computational pipelines for multi-omics analysis
  • Collaborate closely with the Screening, Genome Engineering, and Protein Engineering teams to design experiments and interpret results
  • Develop and maintain internal databases and infrastructure to ensure experimental results are accessible, reproducible, and actionable

Requirements

  • PhD with 5+ years or Master's with 10+ years (or Bachelor's with 12+ years) of industry experience in Computational Biology, Bioinformatics, or a related quantitative discipline.
  • Excellent organizational, communication, and documentation skills, with demonstrated ability to work effectively in collaborative, interdisciplinary environments
  • Strong scientific critical thinking skills, including the ability to evaluate approaches, synthesize complex data, and provide actionable recommendations
  • Strong expertise in experimental design, data processing, statistical analysis, and NGS data analysis

Skills

  • Expert-level proficiency in Python and/or R, with extensive experience using data science libraries (e.g., Pandas, NumPy, Bioconductor)
  • Experience with cloud computing platforms for large-scale data processing and with workflow management systems
  • Proven track record of working successfully across cross-functional teams with proactive communication and timely delivery
  • Qualifications & Skills:

Compensation

  • $180,000 - $195,000

Company info

  • Stylus Medicine is developing transformative in vivo genetic medicines to unlock cures.
  • Stylus combines engineered recombinases with non-viral delivery to specifically encode therapeutics.
  • The company's approach is versatile and modular, with potential therapeutic application across oncology, autoimmune, genetic diseases, and beyond.
  • Stylus Medicine is seeking an innovative, intellectually curious and team-oriented Principal Scientist to support our large serine recombinase (LSR) engineering platform.

This listing is sourced directly from Stylus Medicine's careers page and normalized into a canonical job model.