Xaira Therapeutics
Director, Protein Sciences
South San Francisco, California, United States · Director
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About the role
- As the Director of Protein Sciences, you are the primary architect of the group's strategic vision.
- You cultivate a culture of scientific rigor, high performance, and rapid iteration.
Responsibilities
- Champion and drive cross-functional integration across diverse research teams-spanning biology, AI design, and engineering-to successfully achieve scientific goals and address complex project demands.
- Direct and optimize protein production from a range of host organisms ( E. coli, cell-free, and mammalian), and a range of throughputs 10 to 1000s at varying volumes.
- Train and mentor junior team members, providing guidance on experimental design, data analysis, and troubleshooting.
- Maintain accurate and detailed records of experiments, protocols, and results in accordance with company standards and regulatory requirements.
- Xaira Therapeutics an equal-opportunity employer. We believe that our strength is in our differences. Our goal to build a diverse and inclusive team began on day one, and it will never end.
- Our goal to build a diverse and inclusive team began on day one, and it will never end.
Requirements
- B.S. or Ph.D in Structural Biology, Protein Biochemistry, or related fields with 10+ years of industrial experience.
- Deep experience in designing and optimizing antibody production processes, including fermentation, cell culture, and purification.
- Experience in using automation to generate high throughput (1000+) small-scale antibodies and related molecules.
- Hands-on experience in utilizing a variety of analytical techniques like HPLC, Mass Spectrometry, BLI, SPR, ELISA, and CE-SDS for antibody characterization.
- You are conscientious, detail-oriented, and organized.
- Collaborate with Process Development to strategize and perform critical experiments required for clinical development.
- Analyzing experimental data, drawing conclusions, and providing insights to inform process optimization
- Working with cross-functional teams, including research, CMC, and clinical, to ensure alignment and successful product development.
- Maintaining detailed documentation of experimental designs, methods, and results in electronic lab notebooks. You are conscientious, detail-oriented, and organized.
- Contributing to the preparation of technical reports and regulatory documentation.
- Training and mentoring junior team members in protein production and analytical techniques.
Nice to have
- Background in structural biology (X-ray crystallography or cryo-EM) is highly desirable.
- Experience using LIMS and Benchling systems.
- however, the base pay offered will vary depending on the market, job-related knowledge, skills and capabilities, and experience.
- Xaira Therapeutics an equal-opportunity employer.
- We believe that our strength is in our differences.
- TO ALL RECRUITMENT AGENCIES: Xaira Therapeutics does not accept agency resumes.
- Please do not forward resumes to our jobs alias or employees.
- Xaira Therapeutics is not responsible for any fees related to unsolicited resumes.
Skills
- About Xaira Therapeutics
- Xaira is an innovative biotech startup focused on leveraging AI to transform drug discovery and development.
- Collectively, these technologies aim to continually enable the identification of novel therapies and to improve success in drug development.
- Xaira is headquartered in the San Francisco Bay Area, Seattle, and London.
Compensation
- We offer a competitive compensation and benefits package, seeking to provide an open, flexible, and friendly work environment to empower employees and provide them with a platform to develop their long-term careers.
- We offer a competitive package that includes base salary, bonus, and equity.
- The base pay range for this position is expected to be $196,000 - $245,000 annually
- however, the base pay offered will vary depending on the market, job-related knowledge, skills and capabilities, and experience.
Benefits
- A Summary of Benefits is available for all applicants.
This listing is sourced directly from Xaira Therapeutics's careers page and normalized into a canonical job model.