Vaxcyte
Staff Engineer, Process Development and Manufacturing
San Carlos, California, United States · Staff+
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odds of building a lasting career here
Sponsors, but it's cap-subject — you still face the weighted lottery (~61% per draw at Level IV). Good if you win; have a cap-exempt backup on your list.
Lottery odds assume a STEM candidate.
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This range already reaches Level IV — the maximum four lottery entries.
DOL prevailing wage, 2026-27 wage year · Industrial Engineers (17-2112) · San Francisco-Oakland-Fremont, CA. Wage level is derived by USCIS from the offered wage, occupation and worksite; the occupation shown is inferred from the job title.
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About the role
- Vaxcyte is a clinical-stage vaccine innovation company engineering high-fidelity vaccines to protect humankind from the consequences of bacterial diseases, which have serious and costly health consequences when left unchecked.
- Working to eradicate or treat bacterial infections such as invasive pneumococcal disease, Group A Strep, and Shigella is just the beginning.
- Our path to success is clear and well-defined, and Vaxcyte is set up to go the distance.
Requirements
- Strong expertise in chromatography, filtration, UF/DF, and downstream processes.
- Experience supporting GMP manufacturing, late-stage clinical or commercial manufacturing programs, process validation, and lifecycle process management (PPQ and CPV programs).
- Experience leading complex technical deviations / investigations, troubleshooting, and root cause analysis.
- Hands-on experience with laboratory-scale and pilot-scale purification operations.
- Strong knowledge of cGMP regulations and manufacturing quality/compliance systems.
- Demonstrated ability to influence matrix teams without direct authority.
Nice to have
- Prior experience with vaccine or conjugate manufacturing processes preferred.
- Experience implementing or supporting implementation of Transitional Analysis for Column Integrity Testing preferred.
Compensation
- $186,000 - $218,000 (SF Bay Area).
- The compensation package will be competitive and includes comprehensive benefits and an equity component.
Benefits
- All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability or veteran status.
Company info
- Join our Mission to Protect Humankind!
- WHAT we do is every bit as important as HOW we do it!
- Our work together is guided by four enduring core values:
- We bring creative and intellectual diversity to every facet of the work we do in order to innovate and re-innovate the way vaccines are delivered.
- We embody our collectively audacious goal to courageously make the most complex biologics ever attempted to protect humankind.
- Everyone leads at Vaxcyte with a kindness-first, inclusive approach to collaboration and vigorous debate that advances our business objectives.
- The magnitude of our challenge requires our shared commitment to demonstrating integrity, accountability, equality and clarity across communications and decision making.
Equal opportunity
- We are an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability or veteran status.
- Recruitment Fraud Notice
- Please be aware of fraud or scams from individuals, organizations and/or internet sites claiming to represent Vaxcyte in recruitment activities. Vaxcyte has an established recruitment process for all positions prior to issuing an offer for employment and we will never extend unsolicited employment offers or ask candidates to provide financial or sensitive personal information as part of the application process. All legitimate communication from Vaxcyte will come from an official @vaxcyte.com email address. Qualified and interested candidates should apply to current openings at vaxcyte.com/careers.
- We are an equal opportunity employer.
This listing is sourced directly from Vaxcyte's careers page and normalized into a canonical job model.