Beam Therapeutics
Vice President, Global RWE and HEOR Strategy
Cambridge, MA · Exec · Full-time
Sponsorship not specified$310k-$400kDetected 68 days ago
Data AnalysisStatisticsEHR/EMRCRISPRResearchCommunicationCollaborationProblem SolvingBiostatisticsEpidemiology
About the role
- Beam Therapeutics is a biotechnology company committed to establishing the leading, fully integrated platform for precision genetic medicines.
- To achieve this vision, Beam has assembled a platform with integrated gene editing, delivery and internal manufacturing capabilities.
- This has the potential to enable a wide range of therapeutic editing strategies that Beam is using to advance a diversified portfolio of base editing programs.
Responsibilities
- Develop, validate, and integrate patient‑centered outcomes (PROs) into protocols and analyses.
- Develop and operationalize external/synthetic control arm approaches (e.g., matched registry cohorts, Bayesian borrowing) for single‑arm or small‑population studies typical in cell & gene therapy.
- Build and maintain economic models (cost‑effectiveness, budget impact) tailored to one‑time CGTs, addressing uncertainty/durability and caregiver burden.
- Collaborate with Market Access to design innovative payment models and outcomes‑based agreements with pragmatic outcomes and tracking.
- Lead the AMCP dossier and pre‑approval information exchange (PIE) strategy (6-12 months pre‑launch).
Requirements
- 20+ years' experience in observational research study management AND data analytics, either within industry or with an observational research consulting firm.
- Master's Degree or higher in Health Economics and Outcomes Research or a relevant discipline.
- Formal training in Epidemiology/Health Services Research required.
- Demonstrated ability to lead in a matrixed, cross-functional environment, combining strategic agility with strong business acumen.
- Independent, proactive operator with strong ownership.
- Cross functional collaboration with Clinical, Regulatory, Commercial, Medical Operations, and Publications while maintaining medical/scientific integrity.
- Excellent communication, collaboration, and problem-solving skills.
- Onsite requirements: Candidates are expected to come onsite 1-3 days per week.
- The salary range below reflects the full-time base salary range we expect to pay for this role at the time of posting. Base pay will be determined based on several factors including, but not limited to, relevant experience, education, scope of job, internal comparisons, and market data.
- Beam Pay Range
- $310,000 - $400,000 USD
Nice to have
- Proven track record in drug development, with rare disease experience and an existing network of hematologists preferred.
Compensation
- The salary range below reflects the full-time base salary range we expect to pay for this role at the time of posting.
Benefits
- Beam is a values-driven organization committed to its people, cutting-edge science, and a vision of providing life-long cures to patients suffering from serious diseases.
- lead development of clinical sections for Investigator's Brochures, briefing books, safety updates, IND/NDA materials, and responses to Health Authority questions.
- Interpret clinical trial results (including PROs and healthcare resource use) and partner with Clinical Development/Biostatistics on Statistical Analysis Plans (SAPs) and post‑hoc analyses.
- contribute to long‑term capability building (digital health, real‑world studies).
- Support Market Access on internal and external payer/policy initiatives (pricing and reimbursement, unmet medical need, regional market dynamics, evidence gaps) across the portfolio.
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