Exel
Senior Scientist I (In Vivo Pharmacology)
Alameda, CA · Senior
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odds of building a lasting career here
Sponsors, but it's cap-subject — you still face the weighted lottery (~45% per draw at Level III). Good if you win; have a cap-exempt backup on your list.
Lottery odds assume a STEM candidate.
Personalize to your clock →H-1B wage level
the lottery is wage-weighted — each level is one more entry
$20,242 more — $147,742 — moves this role to Level III and 3 lottery entries. That figure is inside the range the employer already advertised.
Based on the DOL prevailing wage for this occupation and worksite, a base salary of $147,742 would place this position at wage Level III. That figure is within the posted range, and I'd like to target it. This role classifies under "Biological Scientists, All Other" for prevailing-wage purposes.
DOL prevailing wage, 2026-27 wage year · Biological Scientists, All Other (19-1029) · San Francisco-Oakland-Fremont, CA. Wage level is derived by USCIS from the offered wage, occupation and worksite; the occupation shown is inferred from the job title.
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Sourced from Department of Labor LCA, PERM and prevailing-wage disclosure data. Employer matching is by name, so figures may be split across an employer's legal entities. Absence of a filing means none appears in our copy of the data, not that none exists.
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About the role
- SUMMARY/JOB PURPOSE (Basic purpose of the job): The Senior Scientist I is responsible for supporting in vivo pharmacology research efforts for various Biotherapeutics projects.
- Our office is a modern space that fosters collaborations and creativity.
- Teams work closely together, sharing ideas and solutions in a supportive atmosphere.
Responsibilities
- Lead, design, execute and interpret in vivo pharmacology (PK/PD/Efficacy) experiments to test the selected compounds in rodent tumor models.
- Provide scientific support for the project teams and Biotherapeutics/Translational Pharmacology staff.
- Utilize literature and internal data sets to design and test hypotheses for drug targets.
- Prepare Pharmacology study reports for research findings and support IND filings.
- Collaborate with the IACUC committee to ensure compliance with internal policies and animal welfare regulations.
Requirements
- The strong candidate must be a highly self-motivated, interactive, and productive hands-on PhD scientist.
- The candidate must have a deep understanding of the concept of PK, PD, and efficacy, and be able to interpret their relationship.
- Expertise in cell culture with aseptic technique and basic in vivo techniques (handling different routs of administration, blood collection, etc.) is a must.
- It is not designed to contain or be interpreted as a comprehensive inventory of all duties, responsibilities and qualifications required of employees assigned to the job.
- Hands-on in vivo work is required with support for external CRO studies when needed.
Skills
- BS/BA in Pharmacology, Cancer Biology, Molecular Cellular Biology or related field and a minimum of 7 years relevant experience; or,
- MS/MA in Pharmacology, Cancer Biology, Molecular Cellular Biology or related field and a minimum of 5 years relevant experience; or,
- PhD in Pharmacology, Cancer Biology, Molecular Cellular Biology or a closely related field and 0 years of relevant experience; or,
- Equivalent combination of education and experience.
- Understanding the regulations and guidelines of IACUC and AAALAC is a must.
- Has flexibility to adapt to a fast-paced work environment and coach junior scientists.
- Excellent oral and written communication and presentation skills.
- Detail-oriented and able to problem-solve and offer potential solutions.
- Advanced knowledge of MS Office,.pdf, GraphPad, Benchling notebook, and Studylog is required.
- Strong scientific expertise with a good track record of publications.
- Experience working with CROs to coordinate and execute studies in a timely manner.
- Knowledge, Skills and Abilities:
Compensation
- The base pay range for this position is $127,500 - $180,500 annually.
- The base pay range may take into account the candidate's geographic region, which will adjust the pay depending on the specific work location.
Benefits
- The base pay offered will take into account the candidate's geographic region, job-related knowledge, skills, experience and internal equity, among other factors.
- Employees are also eligible for a discretionary annual bonus program, or if field sales staff, a sales-based incentive plan.
- May require weekend and holiday work to support in vivo studies.
This listing is sourced directly from Exel's careers page and normalized into a canonical job model.