Kiniksapharmaceuticals

Kiniksapharmaceuticals

Manager, Product Complaint

Lexington, MA

Sponsorship not specifiedDetected 12 days ago
ExcelGMPFDA RegulatoryPharmacovigilanceCommunicationCollaborationMicrosoft OfficeRegulatory Affairs

About the role

  • Grounded in rigorous science and bold innovation, the company fosters a highly collaborative, patient‑first culture led by accomplished life sciences leaders.
  • At Kiniksa, talented individuals are trusted and empowered to make a real impact-shaping the future of medicine while improving the lives of patients who need it most.
  • This role is accountable for ensuring the product complaint handling process remains compliant, inspection ‑ ready, and aligned with patient safety and regulatory expectations at all times.

Responsibilities

  • Manage and perform complaint intake, triage, investigation, and closure, documenting all activities accurately and contemporaneously within the electronic Quality Events system.
  • Initiate, document, and implement Corrective and Preventive Actions (CAPAs) when complaint trends, investigations, or risk assessments warrant action, in accordance with established procedures.
  • Ensure appropriate training is delivered to relevant employees and vendors; develop and deliver product complaint training and periodically assess and update training materials to ensure effectiveness.
  • Maintain accurate complaint metrics and tracking tools and provide periodic status reports and trend summaries to Senior Management.
  • Maintain and execute complaint handling processes and procedures to ensure compliance with internal quality system requirements and applicable global regulations and standards.
  • Maintains a strong commitment to patient safety by ensuring accurate evaluation, documentation, and timely reporting of complaints and adverse events.
  • Understanding and familiarity with GMP regulations, including 21 CFR 210 and 211, ICH guidelines, FDA guidance documents
  • Kiniksa Pharmaceuticals is a commercial‑stage biopharmaceutical company developing and commercializing novel therapies for diseases with unmet need, with a focus on cardiovascular indications.
  • With deep expertise in immunology and inflammation, Kiniksa is advancing a growing portfolio of approved and investigational medicines, anchored by its lead product, ARCALYST®, the first and only FDA‑approved therapy for recurrent pericarditis.

Requirements

  • Requires a Bachelor of Science degree in scientific field (e.g., Biology, Chemistry) with 5+ years' experience in a GMP biopharmaceutical setting
  • A proactive, detailed oriented person, with experience in leading and authoring product complaint investigations, and the ability to clearly and accurately present information in writing
  • Proven mindset of proactive continuous improvement

Benefits

  • Communicate directly with complainants (e.g., patients, healthcare providers, distributors) to obtain complete and accurate information necessary to support product complaint investigations.
  • Coordinate and actively participate in the escalation of product complaints, including cross‑ functional collaboration with Quality, Manufacturing, Regulatory Affairs, Medical Safety, and Technical teams.
  • Perform monthly reconciliation of product complaints and adverse event/safety information with Global Medical Safety / Drug Safety to ensure accurate and complete regulatory reporting.
  • Partners with Quality, Manufacturing, Regulatory, and Medical Safety teams to escalate, resolve, and continuously improve complaint management processes.

This listing is sourced directly from Kiniksapharmaceuticals's careers page and normalized into a canonical job model.