Convergent Research

E11 Bio - Senior Research Associate - in vivo

Alameda, California · Senior

Sponsorship not specified$90k-$144kDetected 180 days ago

ResearchAnimal StudiesCommunication

About the role

E11 Bio is a non-profit Convergent Research focused research organization located in Alameda, California, pursuing blue-skies neuroscience research yet operating like a nimble, tight-knit start-up.
High quality tissue samples are the foundation of our science.
This role is responsible for executing and continuously improving perfusion, fixation, and injection protocols, including preparation of perfusates and active troubleshooting of tissue-quality issues.

Execute and support in vivo surgical workflows, including stereotaxic and retro-orbital viral injections, post-operative monitoring, and animal welfare documentation.
Apply scientific training to monitor, control, and systematically optimize key in vivo and perfusion parameters for tissue labeling + preservation.
Collaborate closely with experimental scientists to design, execute, and troubleshoot in vivo labeling experiments, contributing technical judgment and experimental insight.
Maintain accurate experimental records, reproducible protocols, and operational readiness of perfusion and surgical equipment.
Demonstrated ability to quickly learn, independently own, and optimize complex biological workflows, including diagnosing and resolving tissue-quality or protocol failures.
Clear communication skills and a proven ability to collaborate effectively within interdisciplinary research teams.
You will own and direct execution and scheduling of perfusions at E11.

Hands-on experience performing animal perfusions using PFA or related fixatives for neuroscience or brain tissue applications, with the ability to produce consistent, high-quality tissue.

Mechanical or technical aptitude for maintaining, adjusting, or troubleshooting perfusion rigs, surgical setups, and related laboratory hardware.
Experience with in vivo surgical techniques such as stereotaxic or retro-orbital viral injections (or strong interest and aptitude to train into these methods).
Familiarity with downstream histology, imaging, or molecular tissue workflows.
Interest in neuroscience and connectomics, with motivation to contribute to technically demanding, high-impact research.
In the first 3 months…
After 2 months: You will be independently performing perfusions and generating consistent, high-quality tissue.
You will be running routine surgeries with good survival and recovery, and managing the colony reliably end-to-end.
You will be routinely producing well QCed tissue.

Excellent medical, dental, and vision insurance through a PPO plan; parental leave.
Generous time off + paid holidays.
Stipend for fitness and wellness activities.
Perform routine animal health checks and husbandry tasks as needed, with attention to health or behavioral changes that may impact experimental outcomes.
Experience with rodent handling, restraint, and basic health assessment in a research setting.

E11 Bio is on a mission to advance connectomics towards whole brain scale for humans and other mammals.
We are a collaborative and interdisciplinary team of scientists and engineers engaged in a neuroscience moonshot project to develop a radical technology platform for scalable mammalian brain mapping.
We are seeking a hands-on in vivo senior technician to take full ownership of our animal perfusions and in vivo workflows.
Working closely with experimental scientists, this person will help design, execute, and debug in vivo labeling experiments, and will play a central role in ensuring the reliability and reproducibility of tissue used for our mission to map the mouse brain.
We strive for a healthy and safe workplace and strictly prohibit harassment of any kind.

E11 Bio, LLC is an Equal Employment Opportunity employer that proudly pursues and hires a diverse workforce.

This listing is sourced directly from Convergent Research's careers page and normalized into a canonical job model.