Nurix Therapeutics
Scientist 1, Bioanalytical - Contract
Brisbane, California
Stay score
odds of building a lasting career here
Sponsors, but it's cap-subject — you still face the weighted lottery (~45% per draw at Level III). Good if you win; have a cap-exempt backup on your list.
Lottery odds assume a STEM candidate.
Personalize to your clock →H-1B wage level
the lottery is wage-weighted — each level is one more entry
$13,231 more — $154,731 — moves this role to Level IV and 4 lottery entries. That figure is inside the range the employer already advertised.
Based on the DOL prevailing wage for this occupation and worksite, a base salary of $154,731 would place this position at wage Level IV. That figure is within the posted range, and I'd like to target it. This role classifies under "Chemists" for prevailing-wage purposes.
DOL prevailing wage, 2026-27 wage year · Chemists (19-2031) · San Francisco-Oakland-Fremont, CA. Wage level is derived by USCIS from the offered wage, occupation and worksite; the occupation shown is inferred from the job title.
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Sourced from Department of Labor LCA, PERM and prevailing-wage disclosure data. Employer matching is by name, so figures may be split across an employer's legal entities. Absence of a filing means none appears in our copy of the data, not that none exists.
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About the role
- Help drive Nurix's drug discovery programs by turning complex biological samples into the high-quality bioanalytical data that guides decisions. You will develop and run LC-MS/MS assays for targeted protein degrader candidates and work closely with pharmacology, chemistry and biology teams.
- Nurix Therapeutics is searching for a motivated Scientist 1 to join our Bioanalytical team. The successful candidate will contribute to the bioanalytical efforts to support Nurix drug discovery programs involving in vivo and in vitro studies. The primary responsibility will be to conduct quantitative bioanalysis for in vivo samples. The scope of the daily
Responsibilities
- Provide bioanalytical support for in vivo PK, PK/PD, efficacy studies, non-GLP toxicology and in vitro studies
- Independently develop LC-MS/MS methods to quantitate small molecules in in vitro and in vivo samples and execute sample analysis
- Independently operate, troubleshoot and maintain LC-MS/MS and analytical equipment
- Participate in multidisciplinary project teams and partner closely with other departments, including pharmacology, chemistry and biology to understand bioanalytical needs for PK support
- Maintain accurate and detailed laboratory notebooks
Requirements
- Ability to think and plan strategically, and excellent interpersonal skills and ability to work in a team environment
- Demonstrated experience in small molecule biomarkers as well as drug candidate bioanalytical assay development/sample quantitative analysis in complex biological matrices using LC-MS/MS
- Proven experience running and troubleshooting LC-MS/MS-based quantitative workflows on Sciex platforms and software
Nice to have
- Experience in targeted protein degradation or heterobifunctional degrader platforms
- Extensive experience with H/UPLC and mass spectrometry
- Extensive experience with sample analysis to support PK, PK/PD, efficacy, distribution, metabolism, and non-GLP toxicology studies
- Excellent oral and written communication skills
- Experience reviewing result files and reports from bioanalytical contract research organizations
- Experience with maintaining detailed up to date lab notebooks and technical documentation
- Strong team orientation
- highly collaborative
Compensation
- $142k-$176k
This listing is sourced directly from Nurix Therapeutics's careers page and normalized into a canonical job model.