Genetix Biotherapeutics

Genetix Biotherapeutics

Sr Scientist, Analytical Sciences

Somerville, MA · Senior · Full-time

Sponsorship not specified$127k-$164kDetected 27 days ago
Process ImprovementGMPqPCRCRISPRFlow CytometryMolecular BiologyProtein AnalysisLeadershipCommunication

About the role

  • This is personal and we approach every challenge with radical care.
  • SUMMARY The Senior Scientist, Analytical Sciences will provide strong hands-on technical leadership from the bench for the internal analytical development functions supporting our company's gene therapy product portfolio.

Responsibilities

  • Analytical Execution & Support
  • Execute and manage analytical workflows internally to support day-to-day project milestones and pipeline progression.
  • Implement analytical strategies within the lab to ensure tight alignment with process development milestones and regulatory guidelines.
  • Partner closely with Process Development to provide rapid, high-quality analytical testing for process optimization, routine characterization, and comparability studies.
  • Provide the technical rigor and execute the characterization assays needed to support strategic, data-driven decisions for process comparability.
  • Lead from the bench in the design, development, qualification, and routine testing of novel analytical assays.
  • Drive innovation in analytical platforms to improve assay sensitivity, throughput, and robustness, specifically tailored for complex cell therapies, including the implementation of bench-top automation.
  • Develop new methods with a "right first time" mentality to ensure seamless, robust transition to a downstream GMP environment.
  • Serve as the primary technical lead for the successful transfer of analytical methods from the internal development bench to external QC testing laboratories.
  • Act as the technical subject matter expert (SME) to support troubleshooting, OOS/OOT investigations, and root-cause analyses with external CDMO/CRO partners.

Requirements

  • or an M.S. with 6+ years of relevant industry experience.
  • Communication: Exceptional verbal and written communication skills, with the ability to clearly translate complex, bench-level analytical data into actionable insights for cross-functional CMC teams.
  • Education: Ph.D. in Biochemistry, Molecular Biology, Analytical Chemistry, or a related scientific discipline with 2-5 years of biopharmaceutical industry experience
  • Technical Expertise: Deep, hands-on mastery of cell and gene therapy analytical techniques (e.g., Multicolor Flow Cytometry, ddPCR/qPCR, Cell-based Potency assays, ELISA). Prior hands-on experience with CD34+ cell lineages and/or viral vector characterization is highly preferred.
  • Track Record: Proven success in developing, optimizing, and transferring assays to external CDMOs/CROs, as well as authoring technical reports used in regulatory filings. Strong troubleshooting capability for complex biological assays is essential.
  • Additional Information
  • The pay transparency range provided below is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. We may ultimately pay more or less than the posted range, and the range may be modified in the future. This role is eligible for an annual bonus and long-term incentive. Actual base salary pay will be based on several factors, including but not limited to experience, skills, relevant education/qualifications, external market, internal equity, and other job-related factors permitted by law.
  • Genetix's total rewards package also provides employees with a comprehensive and competitive benefits suite to support a variety of employee needs. These benefits include comprehensive health, life and disability insurance, employer-matched 401(k) plan, lifestyle spending account, flexible time-off + paid holidays and winter holiday period, tuition reimbursement & loan repayment assistance, paid parental leave, paid onsite parking, commuter subsidy, and much more.
  • Pay Transparency
  • $127,000 - $164,000 USD
  • Genetix is proud to be an equal opportunity employer, seeking to create a welcoming and diverse environment. All applicants will receive consideration for employment without regard to race, color, religion, gender, gender identity or expression, sexual orientation, national origin, genetics, disability, age, veteran status or any other applicable legally protected characteristics.

Nice to have

  • Deep, hands-on mastery of cell and gene therapy analytical techniques (e.g., Multicolor Flow Cytometry, ddPCR/qPCR, Cell-based Potency assays, ELISA).
  • Prior hands-on experience with CD34+ cell lineages and/or viral vector characterization is highly preferred.
  • Technical Expertise: Deep, hands-on mastery of cell and gene therapy analytical techniques (e.g., Multicolor Flow Cytometry, ddPCR/qPCR, Cell-based Potency assays, ELISA).

Compensation

  • $127,000 - $164,000 USD
  • The pay transparency range provided below is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting.

Benefits

  • This role is eligible for an annual bonus and long-term incentive.
  • Genetix's total rewards package also provides employees with a comprehensive and competitive benefits suite to support a variety of employee needs.

Company info

  • Our innovation is rooted in the diversity of our teams and results are achieved through cooperation and the integration of multiple viewpoints.
  • Scientist, Analytical Sciences
  • At Genetix Biotherapeutics every role has meaning, every team member is respected, and every day is a chance to make a difference.
  • When you join Genetix, you're not just landing a new role, you become part of a company that's pursuing curative gene therapies to give patients and their families more days.
  • About Genetix Biotherapeutics

Equal opportunity

  • Genetix is proud to be an equal opportunity employer, seeking to create a welcoming and diverse environment.
  • equal opportunity employer, seeking to create a welcoming and diverse environment.
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