Sarepta

Sarepta

Director, AI Architecture & Governance

Cambridge, MA · Director

No sponsorship$206k-$258kDetected 30 days ago
Machine LearningLLMsCRISPRLeadershipCommunicationCollaboration

About the role

  • The promise of genetic medicine has arrived, and Sarepta is at the forefront.
  • In 2023, we launched our fourth therapy and the first ever gene therapy to treat Duchenne.
  • Success requires strong cross-functional collaboration and communication across scientists, engineers, data teams, and executive stakeholders.

Responsibilities

  • Define and maintain the enterprise AI reference architecture (data, model, orchestration, and integration patterns) to support scalable delivery across R&D, clinical, and operations.
  • Lead build vs. buy vs. partner decisions and define approved tooling and platform patterns for AI/ML and agentic capabilities.
  • Define data access and security models for AI systems and partner with EDS to ensure alignment with data governance standards, data ownership, and data quality controls.
  • Maintain oversight of the AI use case portfolio to ensure consistent execution against standards and measurable outcomes; business stakeholders set prioritization.
  • Support for Caregivers

Requirements

  • This role establishes the standards, platform/tooling strategy, and governance frameworks required to deliver AI outcomes safely and at scale, while enabling AI/ML engineering resources to execute efficiently.

Nice to have

  • BA/BS degree with 12+ years of related experience
  • MA/MS degree with 10+ years of related experience
  • 8+ years of experience in AI/ML, data platforms, or enterprise architecture roles, including ownership of reference architectures and cross-team standards.
  • Experience evaluating platforms/tools and driving adoption in complex enterprise environments.
  • Bachelor's degree required
  • advanced degree in a quantitative or technical field preferred.

Skills

  • Strong understanding of AI/ML system architecture and integration patterns.
  • Experience with modern data platforms and cloud architectures.
  • Knowledge of governance, security, and access control models for enterprise data and AI systems.
  • Ability to define scalable patterns for model lifecycle management, auditability, and operationalization.
  • Soft Skills
  • Track record of influencing cross-functional teams without formal authority.
  • Execution-oriented leadership-able to translate standards into practical implementation patterns.
  • Preferred
  • Experience in biotech/pharma and familiarity with R&D and clinical workflows.
  • Experience working in regulated environments, including collaboration with CSV/quality organizations.
  • Experience partnering with data governance organizations on data ownership, quality, and access controls.
  • What Now?

Compensation

  • The targeted salary range for this position is $206,000 - $257,500 per year.

Benefits

  • ​Financial Wellness

Company info

  • The Opportunity to Make a Difference

Visa & Work Authorization

  • Candidates must be authorized to work in the U.S.

This listing is sourced directly from Sarepta's careers page and normalized into a canonical job model.