Moderna
Sr. Director, Head, Quantitative Systems Pharmacology
Cambridge, Massachusetts, USA · Director · Contract
No sponsorship$197k-$353kDetected 28 days ago
MATLABPharmacologyBioinformaticsCRISPRResearchExperimental DesignAnimal StudiesLeadershipCommunicationCollaborationMentoring
About the role
- Moderna's Clinical and Quantitative Pharmacology (CQP) function is seeking an innovative, collaborative, and strategic leader to serve as Senior Director, Head of Quantitative Systems Pharmacology (QSP) capability.
- In this role, you will provide strategic, scientific, and operational leadership for Moderna's mechanistic and systems pharmacology capabilities.
- You will also represent Moderna as a thought leader in QSP and translational modeling.
Responsibilities
- Develop and implement QSP strategy across priority therapeutic areas and modalities.
- Partner with discovery, preclinical, clinical and platform teams to ensure quantitative and biological hypotheses guide experimental design and portfolio advancement.
- Lead design, development, and application of mechanistic models (disease progression, target engagement, immune dynamics, biomarker relationships, etc.) to inform key program decisions.
- Integrate multi-dimensional data and knowledge into multi-scale mechanistic models for translation and decision support.
- Collaborate closely with Clinical Pharmacology, Translational Medicine, DMPK, research, bioinformatics, clinical development and platform sciences to design integrated quantitative strategies.
- Embed QSP principles and deliverables into Moderna's R&D decision framework, including target validation, animal study design, human dose projection, and mechanism-of-action understanding.
- Provide scientific and functional leadership for QSP activities across internal contributors, matrix partners, external vendors, and academic collaborators.
Compensation
- The salary range for this role is $196,700.00 - $353,400.00.
Benefits
- Provide QSP input for INDs, IBs, regulatory filings, and Health Authority interactions.
- Foster an inclusive, collaborative culture that promotes learning, creativity, and scientific excellence.
Visa & Work Authorization
- thout regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry or citizenship, ethnicity, disability, military or protected veteran status, genetic information, sexua
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This listing is sourced directly from Moderna's careers page and normalized into a canonical job model.