pliant-therapeutic

Research Associate II – Translational Sciences (Contract)

South San Francisco · Mid · Contract

Sponsorship not specifiedDetected 61 days ago

ComplianceClinical Laboratory TechniquesPCRMolecular BiologyCell CultureResearchProtein AnalysisWestern Blotting

About the role

Pliant Therapeutics is a clinical-stage biopharmaceutical company and leader in the discovery and development of novel integrin-based therapeutics.
Integrins are a crucial link between a cell's internal structure and its external environment and function in cell signaling, regulation and adhesion as well as wound healing and immune response.
Description We have an immediate opening for a contract Research Associate within our Translational Sciences group.

Learn new laboratory techniques, troubleshoot experiments, and ensure experiments are well-designed and performed to a high standard
Make detailed observations, analyze data promptly, and maintain accurate records
Provide support for various research team projects and lab needs based using dynamic prioritization
Our approach involves developing novel integrin-based therapeutics to treat solid tumors and other diseases.
The primary responsibility of this position will include processing samples, developing, troubleshooting and optimizing assays.

To perform this job successfully, an individual must be able to perform each essential duty.
The requirements listed below are representative of the knowledge, skill, abilities, and prior experience required.
BA/BS degree in Molecular Biology, Biochemistry, Immunology, Cell Biology or related field with a minimum of 3+ years full time laboratory experience in an industry or academic setting.
Practical experience in common cell biology laboratory procedures including cell culture, transfection, qRT-PCR, ELISA, Western blot, immunofluorescence-based staining is a must.
Having experience with running Nanostring, MSD, and/or working with oligonucleotides is an advantage
Ability to evaluate and clearly communicate results both verbally and in written form
Ability to thrive in a culture of respect, accountability, transparency, and collaboration.
Practical experience in common cell biology laboratory procedures including cell culture, transfection, qRT-PCR, ELISA, Western blot, immunofluorescence-based staining is a must. Having experience with running Nanostring, MSD, and/or working with oligonucleotides is an advantage
Comfortable working with ex vivo tissues e.g. human, NHP, and rodent tissues
Candidate should be flexible with rapid changes in schedule based on scope/prioritization of projects
Candidate should exhibit strong, positive attitude for teamwork and learning

Experience working with a variety of primary human and immune cells is preferred

Launched in 2016 by Third Rock Ventures, a leading healthcare venture capital firm, Pliant has developed an industry-leading proprietary library of over 15,000 integrins that serve as a key driver to its portfolio.

Based in South San Francisco, California, Pliant was founded in 2015 to develop therapeutics to modulate specific pathways upregulated or dysfunctional in certain diseases.
Founded by a team of world-renowned researchers from the University of California, San Francisco, this group discovered key insights into the integrin biology and developed small molecule therapeutics to target this devastating disease process.
We believe our platform may be broadly applicable across multiple disease areas including delivery of drug payloads to cells utilizing integrin receptor-binding molecules as tissue-specific delivery and internalization mechanisms.

This listing is sourced directly from pliant-therapeutic's careers page and normalized into a canonical job model.