Roche

Roche

Scientist 3 - Translational Medicine (Ophthalmology- Glaucoma)

South San Francisco

Sponsorship not specified$100k-$186kDetected 8 days ago
PythonData ScienceClinical TrialsPharmacologyBioinformaticsqPCRMolecular BiologyNGSCell CultureResearchLab ResearchProtein AnalysisAnimal StudiesCommunicationProblem SolvingTime ManagementPublic SpeakingBiostatistics

About the role

  • We are seeking a talented and highly motivated Scientist 3 to join Genentech's Translational Medicine (TM) team on-site at our South San Francisco campus.
  • It is a hands-on, high-impact opportunity for a scientist eager to apply their training to help establish a new disease area for Genentech and navigate the complexities of ophthalmic drug development within a deeply collaborative environment.
  • As an integral member of our dynamic team, you will:

Responsibilities

  • Develop and qualify custom assays (e.g., Simoa, NULISA) for biomarkers of interest, moving beyond standard commercial kits to build bespoke solutions for pipeline programs.
  • Design and execute experiments using disease-relevant in vitro human cell models to translate data-driven insights into functional biology.
  • Lead and coordinate exploratory clinical studies in partnership with internal and external collaborators to discover and qualify translational biomarkers.
  • Collaborate closely with cross-functional R&D partners, including Research Biology, Computational Sciences, Tissue Genomics & Proteomics, Biostatistics, Clinical Pharmacology, and Bioanalytical Sciences.

Requirements

  • The ideal candidate will bring:

Nice to have

  • A PhD in Biological Sciences (including neuroscience, immunology, retinal biology, or a related field) with 0-4 years of relevant post-graduate experience.
  • Clinical/translational experience, especially in glaucoma and/or retinal diseases is highly desirable.
  • A proven track record of executing both wet lab experiments and bioinformatic analyses, as demonstrated through a strong peer-reviewed publication record.
  • Computational proficiency with hands-on experience programming in R or Python to apply biostatistical and bioinformatics methods to high-dimensional datasets.
  • Deep technical wet-lab expertise in preclinical/clinical sample analysis and molecular biology techniques (including cell culture, ELISA, qPCR, and NGS/transcriptomics).
  • Outstanding organizational and teamwork skills, including strong time management and a proven ability to thrive in a fast-paced environment.
  • Communication excellence, featuring exceptional oral and written presentation skills, a creative approach to problem-solving, and a clear passion for translating science into life-changing therapies.

Compensation

  • The expected salary range for this position based on the primary location of California is $100,400 -186,400.

Equal opportunity

  • equal opportunity employer.
  • If you have a disability and need an accommodation in relation to the online

This listing is sourced directly from Roche's careers page and normalized into a canonical job model.