ImmunityBio
Scientist I, Research &Development
Louisville, CO
Sponsorship not specifiedDetected 29 days ago
Data AnalysisExcelProcess ImprovementGMPMolecular BiologyCell CultureResearchAnimal StudiesCommunicationProblem SolvingWritingMicrosoft Office
About the role
- The Scientist I position will aid in the development and generation of new novel therapeutics/vaccines intended for pre-clinical and cGMP-manufacturing use.
- The role is responsible for performing research and development work related to numerous expression system-based immunotherapies, including viral vector platforms and mRNA.
- The role will primarily be involved with the cloning of new gene-therapy vectors, subsequent vector characterization, cell culture optimization, and troubleshooting issues related to such pre-clinical manufacturing processes.
Responsibilities
- ImmunityBio, Inc. (NASDAQ: IBRX) is a commercial-stage biotechnology company developing cell and immunotherapy products that are designed to help strengthen each patient's natural immune system, potentially enabling it to outsmart the disease and eliminate cancerous or infected cells.
- Our scientists are working to develop novel therapies that harness that inherent power by amplifying both branches of the immune system, attacking cancerous or infected cells today while building immunological memory for tomorrow.
- This role is also responsible for aiding in the design and execution of product development experiments that lead to a robust and scalable clinical and commercial production process.
- Support Research and Development projects designed to generate pre-clinical material characterization, design of experiments (DOE), and defining critical process parameters.
- Identify and propose process optimization, continuous improvement projects and support initiatives.
- Support scale-up and technology transfer of new products and processes into cGMP manufacturing.
- Support product specific data trending programs.
- Provide support and technical insight for process-related issues and investigations, including non-conformance product impact assessments, root cause analysis, change control, and process optimization.
- Design and execute experiments, and compile results/statistical data analysis for scaled-down lab processes to enable process troubleshooting, support process robustness and characterization studies, and develop process improvements
- Support the lab by performing activities such as maintaining lab equipment, ordering and stocking supplies, and maintaining inventory
Requirements
- Bachelor's degree in Cell Biology, Microbiology, Biology, or other life science or related field with 10+ years of experience including direct experience in upstream and/or downstream processes
- Experience with molecular cloning, human tissue culture, and viral vector construction required
- Experience working with viruses in a BSL-2 viral laboratory required
- Experience in molecular biology/cloning, RNA biology, cell biology, tissue culture and cell-based methods, with a proven track record of achievement required
Compensation
- The annual base pay range for this position is below.
Visa & Work Authorization
- race, gender, color, disability, national origin, age, religion, union affiliation, sexual orientation, veteran status, citizenship, gender identity and/or expression, or other status protected by law
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This listing is sourced directly from ImmunityBio's careers page and normalized into a canonical job model.