Crescent Biopharma

Crescent Biopharma

Vice President, Pharmacovigilance

Waltham, MA · Exec

Sponsorship not specified$323k-$357kDetected 13 days ago
Product ManagementFDA RegulatoryPharmacovigilanceLeadershipCollaborationRegulatory Affairs

About the role

  • For more information, visit www.crescentbiopharma.com and follow the Company on LinkedIn and X.
  • This role may be based in a hybrid capacity from our Waltham, MA office or remotely from the East Coast.
  • This includes being responsible for the strategic oversight and execution of all safety and pharmacovigilance activities, ensuring compliance with global regulatory standards.

Responsibilities

  • Lead and build our Safety and Pharmacovigilance function
  • Establish and maintain a safety and pharmacovigilance infrastructure that prioritizes "safety by design" in all development activities.
  • Oversee the preparation and review of safety documents, including DSURs, safety reports, and clinical development documentation.
  • Ensure compliance with global safety regulations and guidelines and lead responses to safety-related inquiries from regulatory authorities.
  • Manage the pharmacovigilance budget and resources, including both internal teams and external contractors.
  • Drive continuous improvement in pharmacovigilance practices, ensuring readiness for regulatory inspections and audits.
  • Collaborate with cross-functional teams, including Clinical Development, Regulatory Affairs, and Quality, to integrate safety considerations into company strategy.
  • Represent the company, externally, building relationships with industry leaders and vendors to enhance our safety and pharmacovigilance capabilities.
  • Strong leadership skills with the ability to mentor teams and lead cross-functional initiatives.
  • The Company's clinical-stage pipeline includes its lead program, a PD-1 x VEGF bispecific antibody, as well as novel antibody-drug conjugates.

Requirements

  • M.D., D.O., or M.B.B.S. required.
  • This role is based in Waltham, MA and you must have experience in the oncology space.

Nice to have

  • BLA/NDA experience highly preferred

Compensation

  • $323k-$357k

Benefits

  • Crescent Biopharma's vision is to build a world leading oncology company bringing the next wave of therapies for cancer patients.
  • Reporting directly to the Chief Medical Officer (CMO), you will be leading and building out the Safety and PV.
  • This involves providing strategic medical oversight, managing safety data, and guiding cross-functional collaboration to integrate safety into all phases of our product lifecycle.
  • Lead all pharmacovigilance activities for our products, including safety surveillance, signal detection, and risk-benefit assessments.
  • Provide strategic safety insights to the CMO and Executive Leadership Team, particularly regarding the risk-benefit profile of company products.
  • Serve as the primary PV representative in interactions with FDA, NMPA, EMA, and other global health authorities, including Type B/C meetings, Health Authority safety queries, and pharmacovigilance inspections.
  • Education & Experience

Company info

  • We are committed to fostering a diverse, inclusive, and equitable workplace where all individuals are valued and respected.

Equal opportunity

  • Equal Opportunity Employer.

This listing is sourced directly from Crescent Biopharma's careers page and normalized into a canonical job model.