AstraZeneca
Clinical Pharmacometrician
US - South San Francisco - CA · Junior
Sponsorship not specified$125k-$187kDetected 4 days ago
PythonMATLABMachine LearningClinical TrialsPharmacologyFDA RegulatorySASResearchExperimental DesignAnimal StudiesLeadershipBiostatistics
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odds of building a lasting career here
59Sponsors, lottery-bound
Cap-exempt (no lottery)0
Sponsors this role100
Entry-level history0
PERM / green-card track0
Lottery odds (Level III)83
Fits your clock70
Sponsors, but it's cap-subject — you still face the weighted lottery (~45% per draw at Level III). Good if you win; have a cap-exempt backup on your list.
Lottery odds assume a STEM candidate.
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About the role
- Title: Clinical Pharmacometrician
- Position Summary:
Responsibilities
- Build MIDD across cell therapy portfolio.
- Partner with project teams (physicians, clinical pharmacology scientists and statisticians, etc.) to build population PK, PKPD, and exposure-response models to support design and interpretation of clinical studies, influence key decisions in research and development, and support regulatory submissions of cell therapy products.
- Develop mechanistic and empirical models, enabling clear decision making, optimized dosing regimen, and streamlined development paths.
- Minimum of 0 - 3 Years of industry drug development experience in pharmacometrics supporting decision-making, dose selection, study design and regulatory interactions.
- Ability to plan and implement pharmacometrics approaches (PopPK, PKPD, exposure-response, QSP, Bayesian/adaptive methods) that drive dose selection and enable go/no‑go decisions.
- Integration of quantitative pharmacology with innovative biomarkers, AI‑enabled analyses, novel endpoints, and adaptive trial design.
- 12-Nov-2026 Our mission is to build an inclusive environment where equal employment opportunities are available to all applicants and employees.
Requirements
- Hands on experience and advanced proficiency in using pharmacometrics software including NONMEM, Phoenix/NLME, R, SAS, Python, MATLAB, etc.
- Knowledge of global regulatory, compliance, processes, standards and issues specific to pharmacometrics.
Compensation
- The annual base pay (or hourly rate of compensation) for this position ranges from $124,713.60 - $187,070.40.USD.
Benefits
- offered include qualified retirement programs, paid time off (i.e., vacation, holiday, and leaves), as well as health, dental, and vision coverage in accordance with the terms of the applicable plans.
- Education and Experience:
Equal opportunity
- If you have a disability or special need that requires accommodation, please complete the corresponding section in the application form.
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This listing is sourced directly from AstraZeneca's careers page and normalized into a canonical job model.