Moderna
Senior Scientist, Chemistry and Delivery Science
Cambridge, Massachusetts, USA · Senior · Contract
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odds of building a lasting career here
Sponsors, but it's cap-subject — you still face the weighted lottery (~61% per draw at Level IV). Good if you win; have a cap-exempt backup on your list.
Lottery odds assume a STEM candidate.
Personalize to your clock →H-1B wage level
the lottery is wage-weighted — each level is one more entry
$26,074 more — $156,874 — moves this role to Level IV and 4 lottery entries. That figure is inside the range the employer already advertised.
Based on the DOL prevailing wage for this occupation and worksite, a base salary of $156,874 would place this position at wage Level IV. That figure is within the posted range, and I'd like to target it. This role classifies under "Chemists" for prevailing-wage purposes.
DOL prevailing wage, 2026-27 wage year · Chemists (19-2031) · Boston-Cambridge-Newton, MA-NH. Wage level is derived by USCIS from the offered wage, occupation and worksite; the occupation shown is inferred from the job title.
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Sourced from Department of Labor LCA, PERM and prevailing-wage disclosure data. Employer matching is by name, so figures may be split across an employer's legal entities. Absence of a filing means none appears in our copy of the data, not that none exists.
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About the role
- We are looking for an accomplished Scientist to spearhead the development of targeted lipid nanoparticle (LNP) formulations within our fast-moving, cross-functional R&D organization.
- In this role you will push the boundaries of LNP self-assembly, engineer delivery systems for both small- and large-molecule payloads beyond the liver and apply state-of-the-art analytical techniques to link structure with biological performance.
- This position is site-based, requiring you to be at Moderna's site full-time.
Responsibilities
- Drive research programs on targeted, extra-hepatic LNP delivery-from hypothesis generation through in-vitro / in-vivo evaluation
- Develop and optimize LNP self-assembly processes; refine composition, payload loading, and surface modifications for tissue and cell-type specificity
- Independently Design and execute experiments; analyze, interpret, and clearly communicate data to multidisciplinary project teams and leadership
- Implement and innovate advanced physicochemical and biophysical characterization methods (e.g., DLS, CryoEM, SAXS, ITC, NMR, nFCM etc) to elucidate structure-function relationships
- Maintain rigorous electronic laboratory notebooks, SOPs, and study documentation consistent with company expectations
- Mentor & collaborate with research associates, and external partners to meet project milestones
- Deep expertise in lipid nanoparticle design, formulation, and characterization; hands-on experience developing targeted or extra-hepatic LNPs preferred
- Demonstrated ability to plan and manage multiple projects in a highly collaborative, fast-paced setting
Requirements
- Ph.D. in Pharmaceutical Sciences, Chemistry, Chemical Engineering, Materials Science, or a related discipline with 2+ years of experience.
- Proficiency with a broad suite of analytical techniques for nanoparticle size, morphology, composition, and stability assessment
Nice to have
- Here's What You'll Bring to the Table (Preferred Qualifications)
Compensation
- The salary range for this role is $130,800.00 - $209,400.00.
Benefits
- Commitment to inclusive teamwork, continuous learning, and high scientific rigor
- Experience with high-throughput methodologies is highly desirable, and familiarity with artificial intelligence and machine learning techniques is considered a strong plus
- Family planning benefits, including fertility, adoption, and surrogacy support
Company info
- The Role We are looking for an accomplished Scientist to spearhead the development of targeted lipid nanoparticle (LNP) formulations within our fast-moving, cross-functional R&D organization.
- By living our mission, values, and mindsets every day, our people are the driving force behind our scientific progress and our culture.
Visa & Work Authorization
- thout regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry or citizenship, ethnicity, disability, military or protected veteran status, genetic information, sexua
This listing is sourced directly from Moderna's careers page and normalized into a canonical job model.