Arrowhead Pharmaceuticals

Associate Scientist II, Discovery DMPK

Madison, Wisconsin, United States · Mid

Sponsorship not specified$70k-$80kDetected 18 days ago

qPCRResearchMass SpectrometryAnimal StudiesCommunicationProblem Solving

About the role

Arrowhead Pharmaceuticals, Inc. (Nasdaq ARWR) is a commercial stage biopharmaceutical company that develops medicines that treat intractable diseases by silencing the genes that cause them. Using a broad portfolio of RNA chemistries and efficient modes of delivery, Arrowhead therapies trigger the RNA interference mechanism to induce rapid, deep, and durable
knockdown of target genes. RNA interference, or RNAi, is a mechanism present in living cells that inhibits the expression of a specific gene, thereby affecting the production of a specific protein. Arrowhead's RNAi-based therapeutics leverage this natural pathway of gene silencing.

Perform LC-HRMS or stem-loop qPCR based quantitative bioanalysis in a variety of biological matrices (fluids and tissues) in support of pharmacokinetics and tissue clearance studies.
Document experimental procedure and results accurately and meticulously.

Bachelor of Science in Chemistry, Biology.
3+ years of lab experience
Self-motivated team player with the ability to thrive in a fast paced, multi-disciplinary, matrixed environment
Experience with high-throughput sample analysis applying bioanalysis assays.
Experience working on oligonucleotides
Self-motivated team player with the ability to thrive in a fast paced, dynamic, multi-disciplinary, matrixed environment
Candidates must have current, valid authorization to work in the country where this role is located.

Using a broad portfolio of RNA chemistries and efficient modes of delivery, Arrowhead therapies trigger the RNA interference mechanism to induce rapid, deep, and durable knockdown of target genes.
RNA interference, or RNAi, is a mechanism present in living cells that inhibits the expression of a specific gene, thereby affecting the production of a specific protein.
Arrowhead's RNAi-based therapeutics leverage this natural pathway of gene silencing.
Arrowhead's corporate headquarters is in Pasadena, CA with research and development teams in Madison, WI & San Diego, CA, and a state of the art manufacturing facility in Verona, WI.
Our employees are nimble, science-driven innovators who are collaborating to bring new therapies to patients in need.
Arrowhead Pharmaceuticals is seeking an Associate Scientist to join the discovery DMPK group in Chemistry Department.

This listing is sourced directly from Arrowhead Pharmaceuticals's careers page and normalized into a canonical job model.