Capable

Capable

Scientist / Senior Scientist, Peptide Chemistry

San Francisco · Senior

Sponsorship not specified$165k-$220kDetected 26 days ago
RF EngineeringMass SpectrometryAnimal StudiesMentoring

> stay_score

odds of building a lasting career here

37Unrated
Cap-exempt (no lottery)0
Sponsors this role0
Entry-level history0
PERM / green-card track0
Lottery odds (Level IV)94
Fits your clock70

No strong sponsorship signal in the public record yet. In the full product we resolve the exact legal entity and show its filing history with a confidence score — treat as unverified until then.

Lottery odds assume a STEM candidate.

Personalize to your clock →

> community_outcomes

No reports yet — be the first to help the next applicant.

About the role

  • We are a vibrant and intensely mission-driven team in San Francisco, comprising members from MIT, Harvard Medical School, Roche, ETH, and Dana-Farber.
  • In an early-stage environment, we value people who can bring clarity to open-ended problems, take ownership of the next steps, and follow through with energy.
  • Capable Labs is a place for ambitious, high-integrity people who want to become dramatically better.

Responsibilities

  • Lead and scale end-to-end peptide synthesis workflows, including sequence design, resin loading, coupling/deprotection cycles, cleavage, purification, and analytical characterization.
  • Run microwave-assisted solid-phase peptide synthesis, maintain the synthesizer, and troubleshoot failed couplings, low crude purity, side products, cleavage issues, and instrument downtime.
  • Design next-round compounds from SAR, in vitro, and in vivo readouts, using potency, stability, and tolerability data to decide what we make next.
  • You're excited to own synthesis end-to-end: designing compounds, running reactions, purifying and characterizing them, and preparing them for testing with care and urgency.
  • You like being close to the biological readout. You want to understand how compounds perform in vitro and in vivo, then use potency and efficacy data to inform the next design cycle.
  • You will be surrounded by people who care intensely about the work, get close feedback from the people making scientific and company-defining decisions, and have room to own increasingly important problems.
  • We support visa sponsorship where appropriate, including O-1, H-1B, J-1, TN, and other employment-based pathways.

Requirements

  • You have 5+ years of hands-on industry experience in organic, medicinal, or peptide chemistry, with strong experimental judgment, deep troubleshooting ability, and a high bar for execution.
  • You enjoy solving problems creatively, iterate fast, and keep the science rigorous.

Compensation

  • $165,000-$220,000 salary, plus equity options with an implied current value of approximately $50,000-$200,000 before exercise cost, taxes, dilution, and liquidity risk.

Benefits

  • $165,000-$220,000 salary, plus equity options with an implied current value of approximately $50,000-$200,000 before exercise cost, taxes, dilution, and liquidity risk.
  • $500+ monthly wellness budget for training, supplements, coaching, recovery, or other tools that help you perform at your best.
  • You will also have access to HSA, FSA, and 401K plans.
  • We read every referral carefully, and if your referral joins Capable, we'll send you a thank-you bonus.

Company info

  • ABOUT THE ROLE We are a vibrant and intensely mission-driven team in San Francisco, comprising members from MIT, Harvard Medical School, Roche, ETH, and Dana-Farber.
  • Compensation will depend on the skills, experience, and scope of impact you bring. If your background, experience, or compensation needs fall outside this range, we are still open to a conversation based on the scope and impact you could bring.
  • If your background, experience, or compensation needs fall outside this range, we are still open to a conversation based on the scope and impact you could bring.

Visa & Work Authorization

  • We support visa sponsorship where appropriate, including O-1, H-1B, J-1, TN, and other employment-based pathways.
Apply directly at Capable →Create a free account for alerts like thisView Capable immigration profile

This listing is sourced directly from Capable's careers page and normalized into a canonical job model.