Novartis Group Companies

Novartis Group Companies

Senior Scientist, Drug Discovery Biology (Target Biology & MoA)

Cambridge (USA) · Senior

Sponsorship not specifiedDetected 8 days ago
Machine LearningData AnalysisData ScienceA/B TestingClinical TrialsClinical ResearchPharmacologyPatient CareCRISPRMolecular BiologyCell CultureResearchExperimental DesignLeadershipCommunicationCollaborationProblem SolvingMentoring

About the role

  • You will operate at the interface of biology and data, contributing to high-impact drug discovery programs.
  • This role offers a unique opportunity to combine deep biology expertise with data-driven approaches in a highly collaborative and innovative environment.
  • The final salary offered is determined based on factors like, but not limited to, relevant skills and experience, and upon joining Novartis will be reviewed periodically.

Responsibilities

  • Design and run functional biology assays relevant to membrane proteins such as GPCRs, ion channels (e.g., signaling, trafficking, functional readouts), selecting the right model and readout for the mechanistic question.
  • Build MoA packages by integrating genetic/pharmacologic approaches, phenotypic, and pathway data
  • Apply digital tools, data analysis, and institutional knowledge to interpret results and refine experimental design.
  • demonstrate foundational AI fluency and responsible use aligned with enterprise expectations. Collaborate effectively with computational partners (data science) to connect model outputs with experimentally testable biology.
  • Support and mentor junior colleagues/students through coaching on experimental design, execution, and scientific thinking.
  • Maintain high-quality documentation in ELN, ensuring reproducibility, compliance, and adherence to safety standards.
  • Build MoA packages by integrating genetic/pharmacologic approaches, phenotypic, and pathway data; propose follow‑up experiments that close key uncertainties and reduce risk in target validation decisions.
  • Collaborate effectively with computational partners (data science) to connect model outputs with experimentally testable biology.
  • Data literacy: comfortable using databases and multiple data sources to support research activities and experimental decisions.
  • Prior exposure to human disease relevant biology, or strong motivation to build depth quickly; interest in remaining cross‑disease‑area adaptable.

Requirements

  • Recent PhD (within last 2 years) in Cell Biology, Molecular Biology, Pharmacology, Biochemistry, Chemical Biology, Systems Biology, Bioengineering, or related discipline.
  • Evidence of strong hypothesis-driven thinking, experimental troubleshooting, and the ability to translate complex biology into clear next experiments.
  • Experience with multi‑modal evidence integration (e.g., genetics + omics + functional assays) for target validation and MoA.

Skills

  • Job Description Summary
  • Clear written and oral communication skills in English; can communicate results to cross‑functional teams.

Compensation

  • $98,700.00 - $183,300.00
  • The salary for this position is expected to range between $98,700 and $183,300 USD annually.
  • The final salary offered is determined based on factors like, but not limited to, relevant skills and experience, and upon joining Novartis will be reviewed periodically.
  • Novartis may change the published salary range based on company and market factors.
  • Your compensation will include a performance-based cash incentive and, depending on the level of the role, eligibility to be considered for annual equity awards.

Benefits

  • Your compensation will include a performance-based cash incentive and, depending on the level of the role, eligibility to be considered for annual equity awards.
  • US-based eligible employees will receive a comprehensive benefits package that includes health, life and disability benefits, a 401(k) with company contribution and match, and a variety of other benefits.
  • In addition, employees are eligible for a generous time off package including vacation, personal days, holidays and other leaves.
  • To learn more about the culture, rewards and benefits we offer our people click here.

Equal opportunity

  • The Novartis Group of Companies are Equal Opportunity Employers.
  • Accessibility and reasonable accommodations
  • The Novartis Group of Companies are committed to working with and providing reasonable accommodation to individuals with disabilities.
  • Please include the job requisition number in your message.
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