Personalis, Inc
Clinical Lab Scientist Supervisor, Lab Operations, 2nd & 3rd Shifts
Fremont, CA · Full-time
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odds of building a lasting career here
Thin sponsorship signal and lottery-bound (~15% per draw). A low-probability bet with your clock running. Prioritize cap-exempt roles and proven entry-level sponsors first.
Lottery odds assume a STEM candidate.
Personalize to your clock →H-1B wage level
the lottery is wage-weighted — each level is one more entry
$1,782 more — $73,882 — moves this role to Level II and 2 lottery entries. That figure is inside the range the employer already advertised.
Based on the DOL prevailing wage for this occupation and worksite, a base salary of $73,882 would place this position at wage Level II. That figure is within the posted range, and I'd like to target it. This role classifies under "Cytogenetic Technologists" for prevailing-wage purposes.
DOL prevailing wage, 2026-27 wage year · Cytogenetic Technologists (29-2011) · San Francisco-Oakland-Fremont, CA. Wage level is derived by USCIS from the offered wage, occupation and worksite; the occupation shown is inferred from the job title.
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About the role
- Personalis is based in Fremont, California.
- Shift(s) Available: - Sunday - Thursday: 10pm - 6:30am (3rd Shift) - Tuesday - Saturday: 10pm - 6:30am (3rd Shift) - Tuesday - Saturday: 2pm - 10:30pm (PM Shift) Training hours may be different from your shift schedule.
- The PM and 3rd shift would be eligible for an additional shift premium.
Responsibilities
- Perform and report clinical laboratory testing on patient samples to aid physicians diagnose and treat patients. This includes the following areas:
- Select, implement, and evaluate quality control materials for statistical process control of laboratory assays.
- Troubleshoot assays and equipment when quality control materials fail to perform as expected.
- Document all corrective actions taken when test systems deviate from established performance specifications.
- We aim to drive a new paradigm for cancer management, guiding care from biopsy through the life of the patient.
- Our highly sensitive assays combine tumor-and-normal profiling with proprietary algorithms to deliver advanced insights even as cancer evolves over time.
- Our products are designed to detect minimal residual disease (MRD) and recurrence at the earliest timepoints, enable selection of targeted therapies based on ultra-comprehensive genomic profiling, and enhance biomarker strategy for drug development.
Requirements
- Minimum 1 year experience in a Lead role is required.
- Bachelor's degree, preferably in sciences or related discipline.
- At least four years of CLS experience in a clinical laboratory environment.
Nice to have
- Preferred Skills: Experience with manual DNA/RNA extractions, manual library preparation, and automated liquid handlers.
Skills
- Experience with manual DNA/RNA extractions, manual library preparation, and automated liquid handlers.
- The hiring range for this position is $72.10 to $81.70 per hour plus applicable shift differential.
- Personalis is an equal opportunity employer and is committed to the full inclusion of all individuals.
- Protecting Our Candidates:
- #LI-KK1 #LI-Onsite
Compensation
- Our full-time regular positions also include an annual performance-based bonus (or a sales incentive plan) and long-term incentive units (equity) provided as part of our compensation package, in addition to a full range of medical, financia
Company info
- At Personalis, we are transforming the active management of cancer through breakthrough personalized testing.
- A key part of the role is supervising team members and ensuring that all laboratory procedures are followed for specimen handling, next-generation sequencing (NGS) processes, test analyses, and the accurate maintenance of patient records.
- As part of this commitment, Personalis will ensure that persons with disabilities are provided with reasonable accommodations.
- Assist in audits by regulatory bodies like CAP and external customers.
This listing is sourced directly from Personalis, Inc's careers page and normalized into a canonical job model.