Antares Therapeutics

Sr. Principal Scientist, Analytical Development (Small Molecule)

Boston, MA · Principal

Sponsorship not specified$205k-$240kDetected 1 day ago

Clinical Laboratory TechniquesAnimal StudiesLeadershipCommunicationProblem SolvingMentoring

About the role

Salary Band: $205,000-$240,000 Location: Downtown Boston, MA Position Overview The Senior Principal Scientist will provide technical leadership of analytical development within the CMC function across the Antares portfolio.

Lead analytical efforts supporting drug substance and drug product development from discovery through commercial readiness
Ensure successful execution of analytical deliverables by leveraging internal capabilities and external partners (e.g., CDMOs/CROs)
Drive alignment between analytical development strategies and overall program objectives
Lead and contribute to cross-functional teams, effectively managing technical issues and risks within a matrix environment
Maintain and advance state-of-the-art scientific and technical expertise, applying innovative approaches to solve complex challenges
Provide oversight and review of analytical development documentation to support regulatory submissions
Establish and manage project plans, timelines, budgets, and resource allocation for analytical activities
Build and maintain strong internal and external collaborations, including partnerships with CDMOs and technical stakeholders

PhD in chemistry, chemical technologies, or related field with 15+ years of relevant industry experience in analytical development within biotech or pharmaceutical settings
Demonstrated expertise in phase-appropriate small molecule analytical method development and validation
Extensive knowledge of advanced analytical principles and laboratory techniques for drug substance and drug product, including application of control strategies across all stages of development
Experience with pre-development activities, including pre-formulation, solid state characterization, and formulations for animal studies
Strong understanding of quality and regulatory guidelines, with experience supporting analytical sections of regulatory submissions
Proven ability to lead in cross-functional matrix environments, set clear goals, and manage tasks, resources, and priorities
Excellent written and verbal communication skills, with strong organizational, planning, and technical problem-solving capabilities
Demonstrated ability to implement new technologies and innovative approaches within development programs
Experience developing and managing project plans, timelines, and budgets across internal and external teams
Proven track record of building effective collaborations with CDMOs, technical leads, and project teams
Prior experience mentoring and potentially managing direct reports

This listing is sourced directly from Antares Therapeutics's careers page and normalized into a canonical job model.