Vertex Pharmaceuticals

Vertex Pharmaceuticals

Manager, Manufacturing Operations (2nd Shift)

Boston, MA · Mid

Sponsorship not specified$120k-$180kDetected 6 hours ago
RecruitingGMPLeadershipCommunicationCollaborationProblem Solving

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odds of building a lasting career here

55Sponsors, lottery-bound
Cap-exempt (no lottery)0
Sponsors this role82
Entry-level history0
PERM / green-card track0
Lottery odds (Level III)83
Fits your clock70

Sponsors, but it's cap-subject — you still face the weighted lottery (~45% per draw at Level III). Good if you win; have a cap-exempt backup on your list.

Lottery odds assume a STEM candidate.

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Employer immigration record

from this employer's Department of Labor filings

Green-card filing pattern in this occupation

Context, not a finding about this posting: of this employer's 17 green-card filings in this occupation, 100% were for a worker who already held the job.

Green-card follow-through: 83%

Of 12 labor certifications old enough to have been used, 2 expired without the employer filing the next step. Median time from filing to decision: 515 days.100% of their filings were for a worker who already held the job.Only certifications past the 180-day window are counted — recent ones cannot have expired yet.

Files H-1B transfers

29 transfer filings in the last year, covering 29 workers. Median labor-condition decision: 7 days. An employer that already files transfers is one that can take over an existing H-1B.

Sourced from Department of Labor LCA, PERM and prevailing-wage disclosure data. Employer matching is by name, so figures may be split across an employer's legal entities. Absence of a filing means none appears in our copy of the data, not that none exists.

Community outcomes

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About the role

  • This role is responsible for defining and directing activities for cell therapy and cell therapy personnel while maintaining organizational balance across the group.
  • This position is accountable for safe, compliant, and efficient cGMP operations, including equipment setup, assembly, operation, disassembly, and cleaning, while providing leadership to supervisors and manufacturing staff.
  • Direct the activities of the group through management of staff, prioritization, and assignment of tasks.

Responsibilities

  • Lead and manage daily manufacturing operations.
  • Provide leadership, direction, and support to Manufacturing Supervisors and frontline manufacturing personnel.
  • Ensure accurate execution, authoring, review, and approval of batch documentation to maintain compliant manufacturing records.
  • Partner with cross-functional teams to support facility operations, maintenance activities, investigations, deviations, change controls, and manufacturing objectives.
  • Maintain the facility in an audit-ready state through adherence to procedures, documentation practices, and inspection readiness standards.
  • Ensure compliance with SOPs, policies, and work instructions to support safe and successful facility operation.

Requirements

  • Experience in pharmaceutical manufacturing operations within a cGMP-regulated environment required.

Skills

  • Strong interpersonal, communication, and organizational skills.
  • Sound understanding of relevant drug development and manufacturing activities, including applicable standard operating procedures (SOPs).
  • Ability to clearly communicate rationale for procedures, practices, and technical approaches.
  • Demonstrated competency in the principles and practice of cGMPs and associated regulatory considerations in a pharmaceutical environment.
  • Solid understanding of process, equipment, and facility validation requirements.
  • Solid understanding of the cGMP framework in both development and commercial pharmaceutical drug product manufacturing environments.
  • Working knowledge of inspection readiness, deviation management, CAPA, change control, and continuous improvement practices.
  • Education and Experience:
  • Bachelor's degree required, preferably in a scientific, technical, or engineering discipline.
  • 4+ years of experience or the equivalent combination of education and experience.
  • Prior people leadership experience required, including experience managing staff, supervisors, and/or manufacturing teams.
  • Prior cell therapy and aseptic manufacturing experience preferred.

Compensation

  • $119,900 - $179,900
  • The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting.
  • This role is eligible for an annual bonus and annual equity awards.
  • Some roles may also be eligible for overtime pay, in accordance with federal and state requirements.
  • Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law.

Company info

  • At Vertex, we embrace continuous learning and encourage employees to stay informed on advances in AI, technology, automation, and industry trends.

Equal opportunity

  • Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at ApplicationAssistance@vrtx.com
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This listing is sourced directly from Vertex Pharmaceuticals's careers page and normalized into a canonical job model.