Draper
Senior Liver Tissue Engineer
Cambridge, MA · Senior · Full-time
No sponsorshipDetected 30 days ago
PythonMachine LearningData AnalysisCybersecurityIntellectual PropertyMechanical DesignPhotographyBioinformaticsqPCRFlow CytometryMicroscopyMolecular BiologyCell CultureResearchProtein AnalysisAnimal StudiesLeadershipCommunicationProblem SolvingTime ManagementMentoringPublic SpeakingOrganizational SkillsMicrosoft Office
About the role
- Draper is an independent, nonprofit research and development company headquartered in Cambridge, MA.
- The 2,000+ employees of Draper tackle important national challenges with a promise of delivering successful and usable solutions.
- From military defense and space exploration to biomedical engineering, lives often depend on the solutions we provide.
Responsibilities
- Develop, optimize, and characterize liver‑specific micro-physiological (MPS) and organ-on-chip models for toxicity, metabolism, and disease‑state studies
- Plan, conduct, and lead technical experiments with Draper's advanced in vitro tissue culture technologies (micro-physiological system or organs-on-chip) in a BSL-2 laboratory
- Create, version control, and maintain SOPs and analytical methods that are fully compatible within Draper's platform technologies
- Collaborate across multidisciplinary teams to execute project plans; mentor and train bench‑level colleagues and foster a collaborative, safety‑first lab culture.
- Troubleshoot experimental challenges in partnership with teammates and project leadership; drive rapid, data-backed decisions to keep projects on schedule
- Drive solutions to complex problems with limited direction.
- Able to provide insight and suggest design modifications based on analysis outcomes.
- Support day‑to‑day lab organization (reagent sourcing, material preparation, equipment upkeep) to keep the MPS workflow running smoothly
Requirements
- Complete all required training, adhere to institutional, governmental, and safety regulations, and champion an environment of compliance
Nice to have
- Complex hepatic co-culture expertise: Experience integrating non‑parenchymal cells (Kupffer, stellate, sinusoidal endothelial) into hepatocyte-based model to recapitulate complex inflammatory and disease phenotypes
- experience with organoid, primary and/or iPSC cultures.
- Advanced in‑vitro system fluency: Proven experience with microfluidic‑based cell and tissue culture platforms (e.g., micro-physiological systems (MPS), organ‑on‑chip).
- Broad technical breadth: Some experience with microbiology (viruses, bacteria, toxins), immunology, synthetic biology, genetic engineering, bioinformatics/data analytics, and/or in silico modeling
- some experience with bio-informatic pipelines for high-content image and omics integration (e.g. R/Python)
- some exposure to in silico PK/PD modeling to link MPS data to in vivo predictions
- familiarity with lab-automation for routine laboratory workflows.
- Strong communication
Skills
- Proposal development: Experience writing innovative R&D proposals for government sponsors (contracts, grants) and secure external funding.
- Professional
- Connect With Draper for Future Opportunities!
- Job Location - City:
- Job Location - State:
- Massachusetts
- Job Location - Postal Code:
- The US base salary range for this full-time position is
Compensation
- The US base salary range for this full-time position is
Benefits
- Please note that the compensation details listed in US role postings reflect the base salary only, and does not include bonuses or benefits.
- All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, disability, age, sexual orientation, national origin, veteran status, or genetic information.
- Within the range, individual pay is determined by work location and additional factors, including job-related skills, experience, and relevant education or training.
Company info
- Collect, interpret, and summarize data; deliver clear and concise presentations to project leads, internal management, external sponsors/customers, and for peer‑reviewed publication
Equal opportunity
- equal opportunity, and reasonable accommodation for individuals with disabilities in employment, its services, programs, and activities.
- To request reasonable accommodation, please contact hr@draper.com.
Visa & Work Authorization
- Applicants selected for this position will be required to obtain and maintain a government security clearance
This listing is sourced directly from Draper's careers page and normalized into a canonical job model.