Roche

Principal Mechanical Engineer, Next-Gen Sequencing Systems, Research & Early Development

Santa Clara · Principal

Sponsorship not specified$110k-$205kDetected 3 days ago

PythonSolidWorksFEACFDMechanical DesignClinical TrialsClinical ResearchBioinformaticsNGSResearchProblem SolvingOrganizational Skills

About the role

You will contribute to technical strategy, providing data-driven recommendations on architecture and technology.
At Roche, we are working to make next-generation sequencing simple and accessible enough for routine use.
By accelerating clinical research, streamlining workflows, and expanding assay menus, we are broadening access to genomic data and lowering barriers to adoption.

You will drive the research and development of various sub-systems, encompassing electro-mechanical, pneumatic, thermal, fluidic, and consumable technologies.
You will collaborate with cross-functional teams to define and manage critical technical interfaces.
You will own sub-systems through verification, integration, and troubleshooting, working closely with System Integration engineers.
You will lead cross-functional design reviews to drive alignment and resolve technical trade-offs.
You will manage design deliverable timelines and contribute to overall project planning.
You will create and maintain comprehensive design documentation.
You will present progress, data, and design trade-offs to stakeholders, clearly articulating the impact of engineering decisions.
A healthier future drives us to innovate.
Let's build a healthier future, together.
You have experience developing next-generation sequencing (NGS) or genomics instrumentation.

You have a degree in Mechanical Engineering, or a closely related discipline, with relevant industry experience (minimum 7+ years for a Bachelor's, 4+ years for a Master's, or 3+ years for a PhD).
You have demonstrated experience designing components for a variety of manufacturing processes (e.g., machining, sheet metal, injection molding, 3D printing).
You have demonstrated problem-solving skills
ability to troubleshoot complex hardware, software, and chemistry interfaces.
You are proficient with machine shop tools, measurement equipment, and rapid prototyping (e.g., CNC mills/lathes, laser cutters, 3D printers).
You have experience solving unique or unpredictable problems that might have an impact on the goals and objectives as set by the organization
You have an advanced degree in Mechanical Engineer, or a closely related discipline
You have a high level of proficiency with Python for device control and data acquisition.
You have experience with simulation tools (CFD, FEA) to guide design decisions.
You have strong interpersonal skills

The expected salary range for this position based on the primary location Santa Clara, CA is $110,400 - $205,400.

Together, more than 100'000 employees across the globe are dedicated to advance science, ensuring everyone has access to healthcare today and for generations to come.
We empower each other to explore new possibilities, foster creativity, and keep our ambitions high, so we can deliver life-changing healthcare solutions that make a global impact.
Relocation benefits are not offered for this role.

Our efforts result in more than 26 million people treated with our medicines and over 30 billion tests conducted using our Diagnostics products.
Roche is an equal opportunity employer.
It is our policy and practice to employ, promote, and otherwise treat any and all employees and applicants on the basis of merit, qualifications, and competence.
The company's policy prohibits unlawful discrimination, including but not limited to, discrimination on the basis of Protected Veteran status, individuals with disabilities status, and consistent with all federal, state, or local laws.
If you have a disability and need an accommodation in relation to the online application process, please contact us by completing this form Accommodations for Applicants.

This listing is sourced directly from Roche's careers page and normalized into a canonical job model.