ratiotx
Radiochemistry Scientist I
Boston, Massachusetts
Sponsorship not specifiedDetected 20 days ago
Computer VisionResearchMass SpectrometryAnimal StudiesCommunicationPublic Speaking
About the role
- About Ratio Therapeutics Ratio Therapeutics is committed to improving and extending the lives of cancer patients without sacrificing their quality of life.
- To accomplish this, we utilize our proprietary TRILLIUM™ and MACROPA™ platforms: TRILLIUM™ allows fine-tuning of radioligand pharmacokinetics, while MACROPA™ simplifies the manufacturing process for the alpha-emitting isotope, actinium-225.
Responsibilities
- Develop radiolabeling methods for small molecules and biologics
- Develop chromatographic methods to analyze and purify radiolabeled compounds (HPLC, GC, radio-TLC, etc.)
- Develop formulations suitable for use in animal and human studies
- Conduct in vitro assays to evaluate and optimize stability of radiolabeled compounds
- Maintain clear and accurate records and perform relevant lab maintenance and calibrations
Requirements
- Ph.D. in chemistry or related field is required
- Working knowledge of organic and analytical chemistry
- Working knowledge of radiochemistry and competency working with radioactive materials
- Strong communication skills, including proficiency in English (both written and oral, as demonstrated by publication record)
- Demonstrated ability to prioritize, multitask, and troubleshoot problems
- Demonstrated ability to readily acquire new skills and techniques
- Must be able to lift 45 lbs. (handling of lead and tungsten vial/syringe shields)
- Some publications in the field
- Ability to work well both independently and as part of a team
Nice to have
- Post-graduate radiochemistry experience is highly preferred (post-doc or otherwise)
- Preferred Skills and Knowledge:
Skills
- Experience with radiometal manual synthesis, including 111In, 68Ga, 64Cu, 90Y, 177Lu, and 225Ac among others
- Experience with radiopharmaceutical manufacturing and testing for animal and/or human use
- Experience working in a CMC environment to help guide preclinical R&D strategy
- In your CV or cover letter, please highlight isotope- and/or target-specific experience.
- About Ratio Therapeutics
- Ratio Therapeutics is committed to improving and extending the lives of cancer patients without sacrificing their quality of life.
- These enabling platform technologies have resulted in an emergent pipeline of novel therapeutic candidates.
- Join us in our quest to become the leading innovator in radioligand therapy and improve the lives of cancer patients and their families.
- About the Position
Compensation
- The annual base salary for this role is expected to range between $105,000.00 and $125,000.00.
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