strandtherapeutics

Scientist / Senior Scientist, Process Sciences and Innovation

Boston, Massachusetts · Senior · Full-time

Sponsorship not specified$120k-$142kDetected 14 days ago

Data AnalysisData ScienceProcess ImprovementMolecular BiologyResearchExperimental DesignAnimal StudiesLeadershipCommunicationPublic Speaking

About the role

This role will help shape the future direction of Strand's mRNA and LNP development capabilities.
Strand Therapeutics is a clinical-stage biotechnology company pioneering programmable mRNA therapeutics to unlock the full potential of genetic medicines.
Strand is advancing a pipeline with an initial focus on oncology and autoimmune disease.

Responsibilities

Own the technology scouting function for Process Development by identifying, evaluating, and championing emerging technologies that have the potential to transform mRNA and LNP development and manufacturing.
Design and execute experimental studies that challenge existing process paradigms and generate new approaches to mRNA synthesis, purification, and LNP formulation.
Partner closely with Analytical Development to develop and implement advanced characterization methods, process analytical technologies (PAT), in-line monitoring strategies, and real-time process understanding tools.
Develop innovative strategies to improve process performance, scalability, reproducibility, and product quality across mRNA and LNP unit operations.
Lead scientific investigations into complex process and product challenges and develop creative, data-driven solutions.
Establish mechanistic understanding of critical process parameters and material attributes through thoughtful experimental design and data analysis.
Build and manage relationships with technology vendors, equipment manufacturers, CROs, academic groups, and industry collaborators to evaluate emerging capabilities and technologies.
Maintain awareness of scientific and technological advances through active participation in conferences, publications, industry forums, and professional networks.
Maintain electronic laboratory notebooks and author technical reports, protocols, presentations, and scientific summaries.

Requirements

B.S. or Advanced Degree in Chemical Engineering, Biochemical Engineering, Pharmaceutical Sciences, Biotechnology, Biochemistry, Molecular Biology, or a related scientific discipline.
Proven track record of identifying, evaluating, and implementing new technologies, methodologies, or workflows that improve process understanding, development efficiency, scalability, or product quality.
Demonstrated ability to think creatively and challenge conventional approaches to solve complex technical problems.
Strong understanding of process development principles and the relationship between process parameters, material attributes, and product quality.
Familiarity with advanced analytical technologies, process analytical technologies (PAT), in-line monitoring, automation, digital process development, and advanced data analysis techniques is highly desirable.
Experience with Design of Experiments (DOE), multivariate analysis, mechanistic process understanding, and data-driven process optimization approaches.
Strong oral and written communication skills with the ability to communicate complex technical concepts to diverse audiences.
Significant industry experience developing mRNA, lipid nanoparticle (LNP), or related nucleic acid therapeutic products, with demonstrated technical leadership and scientific innovation.
Experience designing and executing experimental studies that generate actionable scientific insights and drive strategic decision making.
Experience collaborating across scientific disciplines, particularly with Analytical Development, Research, Manufacturing, and external partners.
Demonstrated ability to independently lead technical initiatives while effectively contributing within a highly collaborative team environment.
Self-motivated, intellectually curious, and passionate about advancing the state of the art in RNA therapeutics and nanoparticle delivery technologies.
Strand offers a fast-paced, entrepreneurial, team-focused small company environment. We also offer a top-notch benefits package (health, dental, life, open PTO, onsite lunch catering, commuter support and more) and work/life flexibility and integration. Being part of the Strand team allows you to become part of a small team that supports professional development while working together to meet Strand's goals.

Nice to have

Deep understanding of DNA/mRNA synthesis, purification, and characterization required, experience with LNPs also is preferred

Compensation

$120,000 - $142,000 annually plus bonus and equity incentives
Pay Transparency Base Salary Range
$120,000 - $142,000 USD

Company info

Founded by MIT synthetic biology pioneers, Strand has raised over $250 million and is headquartered in Boston, MA.

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