Flagshippioneeringinc

Flagshippioneeringinc

Scientist I, Formulations

Cambridge, MA USA

Sponsorship not specified$100k-$127kDetected 7 days ago
ComplianceRecruitingIntellectual PropertyThermal AnalysisMicroscopyResearchExperimental DesignCommunicationAdaptability

About the role

  • This role will support our formulation and product development efforts, with a primary focus on the development, screening, and optimization of dried powder formulations.
  • The Scientist I/II will work closely with process development partners to produce robust, stable, and scalable powders.
  • In addition to executing experiments, this role will contribute to experimental design, data interpretation, and the establishment of best practices for formulation screening, characterization, and documentation in a fast-moving, early-stage environment.

Responsibilities

  • Design, execute, and optimize dried powder formulations using lyophilization and spray drying, with a focus on stability, reproducibility, and performance across multiple formulation variables
  • Execute formulation screening efforts using statistically grounded experimental designs (e.g., DoEs), including selection of factors, responses, and experimental conditions, and translate results into actionable next steps
  • Support process development and scale-awareness by documenting critical parameters, identifying sources of variability, and generating data relevant to future scale-up, tech transfer, or external partnerships
  • Maintain clear, rigorous experimental documentation and generate high-quality summaries, figures, and datasets suitable for internal decision-making, patent disclosures, and external communication
  • Contribute to the establishment of long-term formulation workflows, best practices, and standards that support platform development in a small, highly collaborative team.

Requirements

  • Demonstrated experience with drying-based formulation techniques, including lyophilization and/or spray drying, and an understanding of how process parameters influence solid-state;
  • Experience designing and executing statistically informed experiments (e.g., DoEs), with the ability to interpret interaction effects and use data to guide experimental iteration;
  • Familiarity with downstream processing operations (e.g., tangential flow filtration and other purification workflows);
  • Proven ability to work independently in a dynamic, early-stage research environment, balancing hands-on execution with thoughtful experimental planning and cross-functional communication;
  • Bachelor's degree (with 10 years of relevant research experience) or Master's degree (with 8 years of relevant research experience), or PhD (with 0 years of relevant research experience) in chemistry, chemical engineering, pharmaceutical sciences, materials science, biotechnology, or a related discipline.
  • Strong grounding in physical chemistry or materials science principles relevant to dried systems, including glass transition behavior, crystallinity, moisture interactions, and excipient effects;
  • Familiarity with analytical and characterization techniques for powders and solid-state materials (e.g., DSC, TGA, particle sizing, microscopy, bulk property measurements), and the ability to select fit-for-purpose methods;
  • Strong scientific documentation and communication skills, with experience generating reproducible records and decision-enabling datasets;
  • Embodies resilience and scientific rigor in pursuing complex technical questions by iteratively testing hypotheses and refining parameters through uncertainty to converge on robust, optimized solutions.
  • Demonstrated curiosity, adaptability, and comfort working across disciplines, with an interest in translating early scientific concepts into robust, scalable technologies.

Compensation

  • Protocos currently offers healthcare coverage, annual incentive program, retirement benefits and a broad range of other benefits.

Benefits

  • vaccinating billions of people against COVID-19, curing intractable diseases, improving human health, preempting illness, and feeding the world by improving the resiliency and sustainability of agriculture.
  • Flagship Pioneering invents and builds platform companies, each with the potential for multiple products that transform human health, sustainability and beyond.

Company info

  • Flagship Pioneering is a bioplatform innovation company that invents and builds companies that change the world.
  • We bring together the greatest scientific minds with entrepreneurial company builders and assemble the capital to allow them to take courageous leaps.
  • What sets Flagship apart is our ability to advance science and technology by uniting innovation, company creation, and capital investment under one roof in a way that is largely without precedent.
  • Our scientific founders, entrepreneurial leaders, and professional capital managers are each aligned around an institutionalized process that enables us to innovate and transform for the benefit of people and planet.
  • Those big leaps in human health, sustainability and beyond exponentially accelerate scientific progress in areas ranging from disease detection and treatment and nature-positive agriculture to novel applications of AI that are driving the creation of new technologies.
  • Many of the companies
  • At Flagship, we accept impossible missions to enable bigger leaps.

Equal opportunity

  • We are an equal opportunity employer.

Visa & Work Authorization

  • California residents have rights under the CCPA/CPRA including to know, delete, and opt out of the sharing of their personal information.
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