ImmunityBio
Principal Scientist, Upstream Process Science
Louisville, CO · Principal
Sponsorship not specifiedDetected 13 days ago
Process ImprovementGMPFDA RegulatoryMolecular BiologyCell CultureResearchCommunicationMentoringWriting
About the role
- This role serves as a technical expert for specific unit operations within the upstream manufacturing process, including both microbial and cell culture seed expansions and bioreactor operations across multiple cell lines.
Responsibilities
- ImmunityBio, Inc. (NASDAQ: IBRX) is a commercial-stage biotechnology company developing cell and immunotherapy products that are designed to help strengthen each patient's natural immune system, potentially enabling it to outsmart the disease and eliminate cancerous or infected cells.
- Our scientists are working to develop novel therapies that harness that inherent power by amplifying both branches of the immune system, attacking cancerous or infected cells today while building immunological memory for tomorrow.
- The Principal Scientist, Upstream Process Sciences role will manage the team responsible for upstream process development, process characterization, and scientific support activities for GMP manufacturing.
- This role is also responsible for designing and executing process development experiments to design a robust and scalable clinical and commercial production process.
- Manage the day-to-day activities of the team to include the hiring and training of new team members, coaching employees and monitoring performance
- Guide and advise other technical staff in risk assessment, Design of Experiments (DOE), process characterization, process validation, and process monitoring activities.
- Provide input for development programs, and collaborate with discovery, formulation, analytical, quality, regulatory and manufacturing teams.
- Perform ad-hoc and cross-functional duties and/or projects, as assigned, to support business needs and provide developmental opportunities.
- Performs ad-hoc and cross-functional duties and/or projects assigned to support business needs and provide developmental opportunities.
Requirements
- Extensive experience in method development, method validation, and method transfer is required.
- Fundamental knowledge of cell and molecular biology, immunology, and/or virology
- Master-level technical knowledge of microbial, cell culture, and harvest operations affecting product quality.
Nice to have
- Opportunity to join a publicly traded biopharmaceutical company with headquarters in Southern California.
- Work with a collaborative team with the ability to work across different areas of the company.
- Ability to join a growing company with professional development opportunities.
- Provide high-level technical knowledge in the development of batch, fed batch, and perfusion processes for inoculum expansion and biologics production operations.
- Provide project coordination and high-level technical expertise in process development, process improvement, scale-up, and tech transfer activities.
- Draft, review and approve technical protocols, reports, and manufacturing deviation investigations.
- Present activities and results interdepartmentally, and to senior management.
- Author and review process-related regulatory submissions.
Skills
- This position works on site, in Louisville, CO.
- Regular work schedule is Monday - Friday, within standard business hours. Flexibility is available with manager approval.
- Occasional travel may be required, up to 10%.
- Health and Financial Wellness Programs
- Employer Assistance Program (EAP)
- Company Paid and Voluntary Life/AD&D, Short-Term and Long-Term Disability
- Healthcare and Dependent Care Flexible Spending Accounts
- 401(k) Retirement Plan with Company Match
- 529 Education Savings Program
- Voluntary Legal Services, Identity Theft Protection, Pet Insurance and Employee Discounts, Rewards and Perks
- Exempt Employees are eligible for Unlimited PTO
- Non-Exempt Employees are eligible for 10 Vacation Days, 56 Hours of Health Pay, 2 Personal Days and 1 Cultural Day
Compensation
- The annual base pay range for this position is below.
Visa & Work Authorization
- race, gender, color, disability, national origin, age, religion, union affiliation, sexual orientation, veteran status, citizenship, gender identity and/or expression, or other status protected by law
Apply directly at ImmunityBio →Create a free account for alerts like thisView ImmunityBio immigration profile
This listing is sourced directly from ImmunityBio's careers page and normalized into a canonical job model.