Biogen
Global Medical Director, Rare Disease ( SMA/ALS), Evidence Generation Lead
Cambridge, MA · Director
Sponsorship not specified$225k-$310kDetected 7 hours ago
StatisticsExcelResearchLeadershipCommunicationPublic SpeakingWritingGxPBiostatisticsEpidemiology
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odds of building a lasting career here
59Sponsors, lottery-bound
Cap-exempt (no lottery)0
Sponsors this role82
Entry-level history0
PERM / green-card track0
Lottery odds (Level IV)94
Fits your clock70
Sponsors, but it's cap-subject — you still face the weighted lottery (~61% per draw at Level IV). Good if you win; have a cap-exempt backup on your list.
Lottery odds assume a STEM candidate.
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About the role
- By leveraging your deep knowledge of rare diseases, and evidence generation, you will directly contribute to shaping the future of personalized outcomes research and medical advancements.
- This is a unique opportunity to make a meaningful impact in a highly matrixed and dynamic environment.
- Strengthen Biogen's scientific leadership in rare neuromuscular disease by advancing registry-derived evidence on treatment optimization, sequencing, durability, biomarker use, novel endpoints, patient identification, access, and long-term outcomes.
Responsibilities
- Design, prioritize, and oversee evidence generation initiatives - including registry-based studies leveraging established disease registries and natural history networks, real-world data analyses, and other complementary evidence sources - to generate long-term safety, effectiveness, and outcomes data.
- Develop and maintain an integrated evidence generation roadmap across rare portfolio, incorporating registries, real-world data, neurofilament light chain (NfL) and other biomarkers, motor function outcomes, and long-term safety surveillance.
- Develop a communication plan
- Lead or contribute to registry protocol development, statistical analysis plans, study reports, publication strategy, data interpretation, and scientific communication plans for SMA and ALS registry programs.
- Support governance and operating rhythms for cross-functional registry evidence review, prioritization, decision-making, budget tracking, and delivery against measurable evidence-generation milestones.
- You bring curiosity, credibility, and sound judgment to complex rare disease questions, and you are energized by building evidence platforms that shape standards of care across regions.
- You thrive in a collaborative environment and excel at building strong partnerships with diverse stakeholders.
Requirements
- Experience serving on or engaging with registry steering committees, scientific advisory boards, or academic/consortium partnerships that govern shared disease registries.
- Deep therapeutic expertise in SMA, ALS, rare neuromuscular disease, neurodegeneration, genetics, or precision neurology.
- Direct experience with SMA and ALS disease registries or natural history networks,
- Advanced degree (MD, PhD, PharmD, or equivalent) with + 7 years of pharmaceutical, medical affairs, or clinical development experience, including substantial experience specific to evidence generation (registries, real-world data, or related methodologies)
- global medical experience preferred.
- Demonstrated, hands-on experience designing, launching, and governing disease registries or natural history studies, including protocol and case report form design, data governance, site/network engagement, and long-term observational or post-marketing surveillance programs.
- Proven track record analyzing registry-derived real-world data (longitudinal outcomes, safety signals, biomarker trends, effectiveness data) and translating findings into peer-reviewed publications, congress presentations, and medical strategy.
- Strong scientific knowledge of rare neuromuscular disease, SMA, ALS, genetics, or biomarkers, with the ability to lead through influence across a complex global matrix of regional teams, cross-functional partners, and registry governance stakeholders.
- Strong communication and project leadership skills, with working knowledge of global medical affairs compliance, Good Clinical Practice, and registry data quality/governance requirements.
- Experience with global evidence roadmaps, lifecycle management, product launches, registries, health outcomes research, comparative effectiveness, and patient-reported outcomes.
- Familiarity with NfL or other biomarkers, intrathecal delivery platforms, genetic testing, newborn screening, treat-to-target frameworks, and rare disease patient identification strategies.
- Experience partnering with registry steering committees, global medical experts, advocacy organizations, academic collaborators, and cross-regional medical teams.
- Strong publication planning, scientific communication, and technical writing skills, including manuscripts, abstracts, congress presentations, advisory board materials, and internal scientific training.
Nice to have
- Preferred Skills
Compensation
- Tuition reimbursement of up to $10,000 per calendar year
Benefits
- Medical, Dental, Vision, & Life insurances
- Fitness & Wellness programs including a fitness reimbursement
- Paid Maternity and Parental Leave benefit
- Synthesize global medical insights, registry data, external evidence, competitive intelligence, and regional feedback to refine evidence priorities and inform medical strategy.
- You are a scientifically rigorous, globally minded medical leader who can connect evidence strategy to real patient impact.
- You work effectively across functions and geographies, translate complex data into actionable strategies, and keep patients, caregivers, healthcare providers, payers, and regulators at the center of every decision.
- Base salary offered is determined through an analytical approach utilizing a combination of factors including, but not limited to, relevant skills & experience, job location, and internal equity.
Company info
- We are a global team with a commitment to excellence, and a pioneering spirit.
- Up to 12 company paid holidays + 3 paid days off for Personal Significance
- 401(k) program participation with company matched contributions
- As a mid-sized biotechnology company, we provide the stability and resources of a well-established business while fostering an environment where individual contributions make a significant impact.
This listing is sourced directly from Biogen's careers page and normalized into a canonical job model.