Prime Medicine
Senior Scientist, mRNA Design & Platform Innovation
Cambridge, MA · Senior · Full-time
Sponsorship not specified$145k-$161kDetected 10 hours ago
Machine LearningIntellectual PropertyBioinformaticsCRISPRMolecular BiologyResearchAnimal StudiesAnimal ModelsCommunicationProblem SolvingPublic Speaking
About the role
- Communicate research findings clearly to internal scientific audiences; contribute to publications, patent filings, and conference presentations that advance Prime Medicine's scientific profile
Responsibilities
- Design and execute well-controlled experiments to probe structure-function relationships in Prime Editing system components; generate clean, interpretable data that drives platform design decisions
- Lead discovery efforts for novel therapeutic approaches and platform-level applications enabled by Prime Editing, beyond core mRNA design, partnering with program and platform teams to advance the most promising directions
- Adhere to all laboratory safety requirements and procedures; author, review, and maintain accurate laboratory notebooks
Nice to have
- Ph.D. in Molecular Biology, Biochemistry, RNA Biology, Chemical Biology, or a closely related field, plus 5+ years of relevant postdoctoral and/or drug discovery research experience
- Experience working in a collaborative, cross-functional research environment with the ability to contribute meaningfully to team science while driving individual workstreams autonomously
- Experience with next-generation or engineered RNA formats (e.g., circular RNA, modified nucleosides, or related modalities) is a plus
- Familiarity with CRISPR-based or other precision gene editing technologies
- Experience translating RNA-based therapeutic technologies from in vitro systems into in vivo animal models, using non-viral (e.g., LNP) or viral (e.g., AAV) delivery systems
- Working knowledge of human biology and animal models of disease as they relate to therapeutic development
- Excellent scientific communication skills, with the ability to present complex findings clearly to diverse audiences and contribute to written scientific outputs
- strong publication and presentation record, with engagement in the broader scientific community (e.g., conferences, scientific societies)
Compensation
- $145,000 - $161,000 USD
Equal opportunity
- Prime Medicine is proud to be an equal opportunity employer.
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This listing is sourced directly from Prime Medicine's careers page and normalized into a canonical job model.