Entrada Therapeutics

Senior Clinical Trial Manager

Boston, MA · Senior

Sponsorship not specified$44k-$601kDetected 8 days ago

GCPClinical TrialsCommunicationCollaboration

About the role

This individual will lead the day-to-day operations, planning, set-up, execution, and closeout of assigned clinical trials.
They will support and oversee the planning and management of the operational aspects, including CRO and vendor oversight, to achieve project milestones and clinical study timelines in alignment with company goals and in compliance with local, ICH, GCP, and company policies and procedures.

Support and manage various study activities, including vendor evaluation and selection, country and site selection, informed consent development and maintenance, eCRF design and implementation, protocols, study plans and manuals, IBs, CSRs
Proactively identify and support resolution/escalation of trial conduct-related issues.
Lead or support cross-functional trial teams, including collaborating with internal team members and external vendors for the planning and execution of clinical trials, through closeout.
Support the review/cleaning and reconciliation of all clinical data, including EDC, PROs, and 3 rd party labs to support timely database lock and the accurate analysis of clinical data.
Partner with relevant stakeholders to develop and implement appropriate study-specific training to all relevant study-related personnel (internal, CRO, Site staff, and other relevant 3 rd parties).
Support development of department documentation, such as SOPs.
Help develop, organize, and maintain study budgets, working with business operations to ensure accurate forecasting.
Support monitoring activities and visit clinical study sites as needed.
Strong experience in the drug development process, including trial design, trial planning and management, and CRO and vendor oversight.
Meaningful Work, Fair Rewards, and Real Support

BA/BS degree with 7 + years of combined experience supporting and independently managing clinical trial activities.
Strong knowledge of ICH/GCP and regulatory requirements, with a strong preference for experience with global trials and EU-CTR.

The Organization
What's happening at Entrada Therapeutics?
2026 represents a catalyst-rich period for Entrada.
These programs are complemented by the ongoing clinical progress of our DM1 collaboration with Vertex (VX-670).
The Perfect Addition to Our Team

At Entrada Therapeutics, we understand that compensation and total rewards are a major consideration when exploring a new opportunity.
When you join Entrada, you'll be part of a mission-driven team with access to comprehensive health, dental and vision coverage
life and disability insurance
"Our approach to compensation is grounded in transparency, equity and performance for the unique contributions each person brings.

Excellent verbal and written communication skills.
Proven ability to work effectively across functions.
Ability to travel approximately 20% of the time, as determined by the needs of the business
This is a US based remote position, with preference given to local New England based candidates. This role will require minimum monthly or quarterly travel to the Entrada Therapeutics Headquarters located in Boston, MA.
At Entrada, our passion for science, our devotion to patients and our values drives our behavior:
Tenacity - We are relentless and persistent in the pursuit of developing therapies for patients.
Creativity - We are creative problem solvers.
Collaboration - We are more than the sum of our parts.
We are relentless and persistent in the pursuit of developing therapies for patients.

Entrada Therapeutics is an equal opportunity employer.
Qualified candidates will receive consideration for employment without regard to race, color, religion, national origin, gender, sexual orientation, gender identity or expression, age, mental or physical disability, and genetic information, marital status, citizenship status, military status, protected veteran status or any other category protected by law.
Third Party Staffing Agencies
Entrada does not accept unsolicited resumes from any source other than directly from candidates.

rientation, gender identity or expression, age, mental or physical disability, and genetic information, marital status, citizenship status, military status, protected veteran status or any other category protected by law

This listing is sourced directly from Entrada Therapeutics's careers page and normalized into a canonical job model.