Every Cure
Head of Clinical Development
Boston, MA · Exec
Sponsorship not specified$250k-$275kDetected 76 days ago
Machine LearningData ScienceStatisticsClinical TrialsClinical ResearchFDA RegulatoryResearchExperimental DesignAnimal StudiesLeadershipCommunicationCollaborationMentoringAdaptabilityGxP
About the role
- Led by a talented leadership team and an outstanding Board of Directors, Every Cure is supported through funding from leading philanthropic organizations like Chan Zuckerberg Initiative, TED's Audacious Project, and ARPA-H.
- Our approach: - AI-Powered Identification: We use advanced artificial intelligence to analyze the world's biomedical knowledge and identify FDA-approved drugs that can be repurposed for untreated conditions.
- Applicants must reside in the state specified at the top of this job posting.
Responsibilities
- Minimum for Head of Clinical Development: 8+ years of clinical development experience post-MD (or equivalent), including service as clinical lead on at least one sponsor-held Phase 2 trial from protocol through database lock.
- Expertise in drug development, clinical trial design (including interventional trials in rare or ultra-rare populations), and clinical decision-making.
- Own study design decisions end-to-end, from scientific rationale through data integrity and analysis.
- Partner on strategic prioritization and dynamic management of Every Cure's diverse portfolio of drug repurposing opportunities, applying a risk-adjusted, impact-oriented lens to maximize outcomes.
- Personally lead CRO and clinical technology vendor selection, contracting input, and ongoing governance (joint steering committees, KPIs, oversight plans) for highest-priority programs.
- Develop and manage resource allocation frameworks across disease areas and therapeutic modalities, ensuring optimal investment of time, talent, and funding toward the most promising interventions.
- Cultivate and manage partnerships with CROs, patient advocacy groups, academic institutions, and regulatory agencies to ensure successful execution and wide-scale impact of therapeutic programs.
- Partner with the Impact lead to provide input and perspective on dissemination and to engage with key stakeholders to ensure medicines reach patients.
Requirements
- Residency in that state is a requirement for consideration and must be maintained for the duration of employment.
- Experience working across more than one therapeutic research area.
- MD or MD/PhD preferred; PhD DO, or PharmD acceptable
Nice to have
- 12+ years of clinical development experience, including prior functional leadership at a sponsor (Executive Director, Head of, or VP level)
- multiple sponsor-held INDs led through Phase 2 or beyond
- direct experience with REMS programs, risk-based monitoring, or similarly complex regulatory programs
- MD or MD/PhD preferred
- PhD DO, or PharmD acceptable
- Preferred for Vice President designation:
Skills
- familiarity with EU CTR a plus.
- Exceptional communication and presentation abilities.
- Demonstrated ability to foster and sustain a collaborative, cross-functional culture grounded in shared organizational mission and values.
- Strategic thinker with a focus on urgency, efficiency, and impact.
- Passionate about Every Cure's mission and values.
- Highly adaptable, thriving in a fast-paced, start-up environment.
- Compensations & Benefits:
- Your paycheck: Competitive salary based on experience, ranging from $250,000 - $275,000 annually.
- Relax and recharge: Generous time off, including paid time off and paid holidays.
- Every Cure is an Equal Opportunity Employer.
Compensation
- Competitive salary based on experience, ranging from $250,000 - $275,000 annually.
- Your paycheck: Competitive salary based on experience, ranging from $250,000 - $275,000 annually.
Benefits
- Health and wellness: Comprehensive plans with medical, dental, and vision coverage, plus a Flexible Spending Account (FSA) for eligible healthcare expenses.
- Future nest egg: A 403(b)-retirement plan with an employer match of 3.5% helps you save for your future.
- We have you covered: Comprehensive paid leave for family and medical needs, ensuring you have the support you need during important times.
- Provide expert counsel to the CSO, President and Scientific Advisory Council on medical strategy, program development, and organizational growth.
- Translate complex medical findings into strategic decisions regarding program continuation, optimization, or sunsetting, based on efficacy, feasibility, and patient impact.
- Promote continuous learning and growth through coaching, training programs, and development opportunities that build both individual capability and team effectiveness.
Company info
- We are dedicated to making our predictive pipeline open-source, fostering collaboration and transparency within the scientific community and unlocking the potential for discovering new treatments.
Equal opportunity
- Equal Opportunity Employer.
Visa & Work Authorization
- Sponsor-side experience running Phase 2 trials (distinct from CRO or academic investigator experience).
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This listing is sourced directly from Every Cure's careers page and normalized into a canonical job model.