Output
Head of Biology
New York HQ 🗽
Sponsorship not specifiedDetected 47 days ago
PythonMachine LearningBioinformaticsMolecular BiologyResearchLab ResearchExperimental DesignLeadership
About the role
- Output has built a biological reasoning model that understands biology at the scale and complexity life actually operates.
- Our model independently learned the principles of molecular interactions, opening up drug treatments that were previously impossible.
- We're already generating therapies that traditional approaches cannot reach.
Responsibilities
- The hardest problems in both AI and biology are being solved here, and there is room for you to own one.
- You own the feedback loop between Output's models and the lab.
- You go deep into specific biological problems, translate what the biology requires into priorities for data and modeling, and manage through CRO partners the experimental cycle that validates model outputs and generates new data.
- You will manage CRO relationships for peptide and molecular synthesis, biological assays, and experimental testing, designing each campaign to generate maximally informative data
- Healthy feedback focused environment to help you strive - leadership will have high expectations, regularly share constructive feedback, support you and help you grow, and welcome receiving feedback and ideas from you
- You own your day-to-day management.
- You have strong programming skills in Python, with experience building computational pipelines and analysis tools
- You are comfortable going deep into unfamiliar biological problem areas and rapidly developing the expertise needed to guide modeling and experimental decisions
- You have experience building tools or writing code that automates biological analysis workflows
Requirements
- You have a PhD in computational biology, biophysics, structural biology, molecular biology, or a related biological field with 3+ years of post-doctoral or industry research experience
- You have deep understanding of protein biology, protein-ligand interactions, and how sequence and structure relate to biological function
- You have experience designing biological experiments and working with CROs for synthesis and experimental validation
- You have structural biology expertise, including protein structure analysis and structure-function relationships
- You have hands-on wet lab experience
- You have experience across multiple therapeutic modalities, including peptides
Compensation
- Competitive salary and equity in a growing, well-funded startup
Benefits
- Competitive salary and equity in a growing, well-funded startup
- Excellent medical, dental, and vision coverage
- You have experience working with protein language models or machine learning applied to biological sequences and structures
- You have experience with active learning or iterative experimental design in a computational biology or drug discovery setting
- You will own the active learning cycle between
Company info
- We foster a culture of ownership.
- We are assembling a team of individuals who are passionate and take pride in their contributions.
- We value practicality and results-oriented thinking.
- We are committed to making a tangible impact on the lives of patients and the broader community.
This listing is sourced directly from Output's careers page and normalized into a canonical job model.