Alumis
Senior Scientist, Chemical Development
South San Francisco · Senior
Sponsorship not specifiedDetected 2 days ago
GMPResearchCommunicationCollaborationProblem SolvingOrganizational Skills
About the role
- Even with treatment innovations of the last two decades, many patients with immunologic conditions continue to suffer - our goal is to fundamentally change the outcomes for these patients.
- The Alumis team is seeking a highly motivated Senior Scientist, Chemical Development to join the Technical Operations / Chemistry, Manufacturing, and Controls (CMC) team at Alumis.
- Organic Chemistry, Chemical Engineering, or related field The salary range for this position is $140,000 USD to $160,000 USD annually.
Responsibilities
- Drive CDMO activities for late-stage drug substance development and manufacturing, including tech transfer, scale-up, process development, and optimization.
- Provide technical guidance and oversight (both internally and externally) to drive the phase appropriate drug substance development.
- Serve as subject matter expert in chemical development and help drive best practices and technical advancements.
- Review and approve cGMP documents, including batch records, change controls, deviations, specifications, validation master plan, validation protocols/reports.
- Document development activities as source reports for regulatory filings.
- Implement best practices and drive continuous improvements in the drug substance development process through technology innovation and problem solving.
- The successful candidate will support process development efforts as well as oversee activities at contract research organizations (CROs) and contract development and manufacturing organizations (CDMOs).
- Ability to travel domestically and internationally (including Asian countries) up to 25% of the time to support ongoing manufacturing activities
Requirements
- PhD. with minimum of 5 years of experience in small molecule drug substance development, including management of external vendors/CDMOs or MS with minimum of 8 years of experience is desirable
- Experience with late-stage drug substance technical transfer
- Experience with control strategy development and capable of utilizing QbD principles to develop commercially viable manufacturing processes
Compensation
- Organic Chemistry, Chemical Engineering, or related field The salary range for this position is $140,000 USD to $160,000 USD annually.
Benefits
- Alumis compensation packages include generous stock option grants for all employees as well as an annual bonus program.
- Health insurance premiums paid at 90% for employee, 80% for dependents
- $100 monthly cell phone stipend
- Unlimited PTO for Exempt employees
Company info
- This salary range is an estimate, and the actual salary may vary based on the Company's compensation practices.
- We are a hard-working, collaborative team on a mission to transform patient's lives-- and we aspire to elevate, challenge and nurture one another along the way.
- Alumis Inc. is a precision medicines company with the mission to transform the lives of patients with autoimmune diseases.
Equal opportunity
- Alumis Inc. is an equal opportunity employer.
This listing is sourced directly from Alumis's careers page and normalized into a canonical job model.