Genentech
Senior Scientist - Translational Medicine (Tumor Microenvironment)
South San Francisco, USA · Senior
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About the role
- As a member of the Translational Medicine team, you will:
- Contribute to cross-functional project teams, ensuring alignment with overall program goals, timelines, and translational objectives.
- Contribute mechanistic understanding of tumor microenvironment dynamics and immune engagement to inform development and translational strategies for next-generation oncology therapeutics, including T cell engager approaches.
Responsibilities
- Develop and execute biomarker strategies for oncology therapeutics from first-in-human through registrational clinical studies.
- Develop and deploy next-generation biomarker assays across clinical programs to support development decisions and translational research efforts in oncology.
- Partner cross-functionally with Research, Clinical Development, Clinical Pharmacology, Biostatistics, Regulatory, and Companion Diagnostics to ensure scientific alignment and enable data-driven decision-making.
- Write and review biomarker- and disease-related sections of clinical protocols, study reports, regulatory documents, abstracts, and manuscripts.
- Interest in leveraging innovative computational approaches, including emerging AI-enabled and agentic AI tools, to support biomarker discovery, translational insight generation, and data interpretation is a plus.
- Strong scientific curiosity with the ability to independently develop hypotheses and translate complex biological observations into mechanistic insight.
- Demonstrated ability to collaborate effectively across diverse scientific disciplines and contribute positively to team culture.
Requirements
- Excellent written and verbal communication skills, with the ability to communicate complex scientific concepts to multidisciplinary audiences.
- Ability to thrive in a collaborative, fast-paced, shifting priorities, and highly dynamic research environment.
- Prior industry drug development experience is not required.
Nice to have
- Strong expertise or scientific interest in tumor microenvironment biology and prostate cancer is preferred.
- 0-3 years of experience with translational research approaches including molecular profiling, multi-omic analyses, spatial biology, single-cell technologies, and/or functional immune assays is preferred.
- Familiarity with computational approaches for biological data analysis
- knowledge of R and/or Python is preferred.
Compensation
- The expected salary range for this position based on the primary location of California is $120,680 - $224,120 of hiring range.
Benefits
- Publish impactful research in leading scientific journals and represent the organization at scientific and medical conferences worldwide.
Company info
- We are particularly interested in highly motivated scientists with strong postdoctoral training who are excited to help bridge discovery science and clinical development in oncology.
Equal opportunity
- equal opportunity employer.
- If you have a disability and need an accommodation in relation to the online
This listing is sourced directly from Genentech's careers page and normalized into a canonical job model.