Parabilis Medicines

Director, Discovery Program Management

Cambridge · Director

Sponsorship not specified$200k-$240kDetected 40 days ago

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About the role

The company has pioneered a new class of alpha-helical peptides - Helicons™ - capable of modulating intracellular proteins that have historically been beyond the reach of conventional medicines.
Zolucatetide is being evaluated in the clinic across multiple Wnt/β-catenin-driven diseases, including desmoid tumors, familial adenomatous polyposis (FAP) and a range of other solid tumor indications.
Beyond zolucatetide, Parabilis is advancing additional Helicon-based programs focused on other challenging targets where we believe our medicines could have life-altering impact.

Project management of multiple late-stage Discovery programs through lead optimization to development candidate nomination.
Build and maintain integrated program timelines, track budgets, and manage resourcing questions across functions.
Drive alignment on program priorities, decision gates, and go/no-go criteria in partnership with scientific leads and senior leadership.
Serve as the primary operational partner to Discovery program teams, facilitating communication and decision-making across Research functions.
Prepare and support program review meetings, including milestone tracking, risk registers, and leadership updates.
30 Acorn Park Drive | Cambridge, MA 02140 | www.parabilismed.com

BSc in a Life Science related field, with 10+ years of drug discovery experience in industry
Project management experience in drug discovery within a pharmaceutical or biotechnology setting, with direct exposure to late-stage Discovery or DC nomination processes.
Strong scientific literacy, with the ability to engage meaningfully with Discovery data and program science.
Proficiency with modern project management and a genuine enthusiasm for leveraging AI tools to improve program execution.

Experience in oncology drug discovery is a plus but not required.
Demonstrated ability to utilize AI tools for day-to-day work
baseline proficiency is expected, and advanced or innovative use of AI is a strong plus.

The base salary range for this position is $200,000-$240,000, depending on experience, qualifications, and internal practices.
Parabilis's total compensation package also includes an annual target bonus, equity, and a comprehensive suite of competitive benefits designed to support our employees' overall well-being.

The company is committed to promoting an inspiring and flourishing working environment for all employees across the business, in all departments, and driving innovation for patient benefit.

We are fiercely independent as a leader in defying the limitations of current therapeutic modalities, and interdependent as a team as we work collaboratively to shift drug discovery paradigms and provide patients with better treatment options.
Patient-focused. We are deeply focused on patient outcomes, and all energy in the company is focused on science as it translates to patient impact.

As an equal opportunity employer, Parabilis Medicines values an inclusive workplace and welcomes applicants of all backgrounds and experiences.

This listing is sourced directly from Parabilis Medicines's careers page and normalized into a canonical job model.