Novartis
Principal Scientist II, Translational Biomarker Strategy Lead
Cambridge (USA) · Principal
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About the role
- Serve as the biomarker representative and single point of contact on assigned DAx project teams.
Responsibilities
- Novartis Biomedical Research is seeking a highly motivated and scientifically accomplished Translational Biomarker Strategy Lead to serve as the biomarker representative and strategic advisor on DAx project teams.
- This role will lead the development and execution of preclinical and translational biomarker strategies from target validation through development candidate nomination and early clinical planning.
- The Biomarker Strategy Lead will partner closely with Biology, In Vitro, In Vivo, Data Science and Biomarker Development to ensure biomarker plans are aligned with key program decisions and support target engagement, pharmacodynamic assessment, patient stratification, and translational decision-making.
- The successful candidate will act as the single point of contact for biomarker strategy within assigned DAx programs, integrating scientific, technical, operational, and external capabilities to deliver execution-ready biomarker plans that enable efficient progression of the portfolio.
- Develop integrated biomarker plans encompassing assays, models, samples, analyses, timelines, and external partnerships.
- Generate translational evidence linking target biology, pharmacology, and biomarkers to support key portfolio decisions.
- Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture
- We strive to create an inclusive workplace that cultivates bold innovation through collaboration and empowers our people to unleash their full potential.
Requirements
- 7+ years of experience in translational research, biomarker strategy, biomarker discovery, or drug development within the pharmaceutical or biotechnology industry.
- Strong understanding of biomarker applications including target engagement, pharmacodynamics, patient stratification, disease activity, and mechanism-based biomarkers.
- Experience leading cross-functional matrix teams and influencing scientific strategy without direct authority.
Compensation
- 114,100.00 - 211,900.00 USD Annual
- The salary offered is determined based on gender-neutral objectives, such as relevant skills, competencies and experience in accordance with the Novartis pay setting policy and upon joining Novartis will be reviewed periodically.
- In addition to your base salary, you may be eligible for a performance-based bonus depending on certain performance parameters.
- Pay equity is a fundamental principle of our employment policy and reflects our commitment to create a diverse, equitable and inclusive environment that treats all employees with dignity and respect, as outlined in our Code of Ethics.
Benefits
- Benefits and compensation may vary by country and are subject to local legal requirements, including provisions of collective bargaining agreements where applicable.
- Read our handbook to learn about all the ways we'll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards
Company info
- Rewards At Novartis, we're committed to reimagining medicine together - and rewarding the people who make it happen.
- The rewards of being part of our team go far beyond base pay and incentives.
Equal opportunity
- Equal Opportunity Employers.
- The Novartis Group of Companies are committed to working with and providing reasonable accommodation to individuals with disabilities.
This listing is sourced directly from Novartis's careers page and normalized into a canonical job model.