Manifold Bio

Manifold Bio

Associate Scientist/Senior Associate Scientist, In Vivo Pharmacology – Study Coordinator

Boston · Senior

Sponsorship not specified$106k-$123kDetected 14 days ago
Full-Stack DevelopmentData AnalysisPharmacologyqPCRFlow CytometryExperimental DesignProtein AnalysisWestern BlottingAnimal StudiesLeadershipCommunicationCollaborationOrganizational SkillsMicrosoft Office

About the role

  • Our team of protein engineers, biologists, and computational scientists works across this full stack to pursue programs both internally and with leading pharma companies.
  • The ideal candidate brings deep in vivo pharmacology expertise, strong cross-functional coordination instincts, and the ability to operate independently in a fast-moving, early-stage environment.
  • We value different experiences and ways of thinking and believe the most talented teams are built by bringing together people of diverse cultures, genders, and backgrounds.

Responsibilities

  • Own end-to-end study coordination across multiple concurrent in vivo programs - from animal ordering and acclimation through dosing, bleeding, necropsy, tissue collection, and downstream handoff
  • Develop and maintain detailed study plans, timelines, and execution schedules - including who does what, when, and how, with clear accountability at every step
  • Serve as the primary point of contact between scientists, VIVO team members, vivarium staff, and external CROs - ensuring alignment on study design, timelines, and deliverables
  • Contribute to study design in collaboration with program leads - including dose selection, group sizes, timepoints, route of administration, and endpoint strategy
  • Perform and oversee hands-on in vivo procedures including dosing (IV, SC, IP, PO), bleeds, perfusion, necropsy, and tissue collection as needed
  • Track and manage animal orders, reagent inventory, and study materials to ensure readiness ahead of each experiment
  • Maintain accurate, organized records and data entry in Benchling and other platforms
  • Demonstrated experience as a study director, study coordinator, or study lead - owning studies end-to-end with accountability for timelines and deliverables
  • If you're excited to build a platform that combines DNA and protein multiplexing technologies, please reach out to careers@manifold.bio.

Requirements

  • Bachelor's or Master's degree in Biology, Pharmacology, Biomedical Science, or related field
  • 5+ years of hands-on in vivo pharmacology experience in a biotech, pharma, or CRO environment
  • Deep proficiency with in vivo techniques: IV, SC, IP, and PO dosing
  • Experience coordinating multiple concurrent studies across different programs and timelines

Nice to have

  • Experience with humanized or disease mouse models
  • Familiarity with NHP study coordination and CRO management
  • Experience with downstream bioanalytical assays - ELISA, MSD, qPCR, western blot, flow cytometry, IHC, IF
  • Familiarity with histology, tissue sectioning, and confocal imaging workflows
  • Experience with Benchling or similar LIMS platforms
  • Exposure to protein therapeutics and other modalities
  • Experience writing detailed study plans, SOPs, and IACUC protocol amendments
  • Comfortable with data analysis tools including GraphPad Prism and Microsoft Office

Compensation

  • Final compensation decisions are made using a consistent leveling framework and consider the candidate's experience, interview performance, and expected impact.
  • $106,000 - $123,000
  • Annual performance-based target bonus
  • Our compensation ranges are reviewed annually to ensure alignment with market trends and internal equity.

Benefits

  • Annual performance-based target bonus
  • Comprehensive medical, dental, and vision coverage
  • Flexible paid time off and holidays
  • This reflects the typical offer range for this role, based on experience, role scope, and internal equity.
  • Perks including on-site gym, onsite lunch, and commuter support
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