10x Genomics

10x Genomics

Staff Mechanical Engineer

Pleasanton, California, USA HQ · Staff+ · Full-time

Sponsorship not specified$179k-$243kDetected 21 days ago
Product ManagementProcess ImprovementIntellectual PropertySolidWorksFEACFDRoboticsMechanical DesignElectrical EngineeringControlsBioinformaticsMolecular BiologyMedical DevicesResearchLeadershipCommunicationCollaborationMentoringThermodynamicsActuators

About the role

  • Changing the definition of sequencing isn't just our tagline - it's a commitment to game-changing advances in the field of genomics.
  • You will feel the 10x difference the moment you enter our offices and labs.
  • What you will be doing As a Staff Mechanical Engineer at 10x Genomics, you will take on full leadership of critical projects and teams.

Responsibilities

  • Technical & Design Leadership
  • Strategic Mechanical Design: Lead the architecture and design of large-scale mechanical systems and critical subsystems for complex biotech devices. Drive multi-disciplinary integration across mechanical, fluidic, electrical, optical, and software domains.
  • Biotech Innovation: Lead the development of novel mechanical approaches to solve complex problems in genomics (e.g., bioprocessing systems, automation platforms, liquid handling, and consumables).
  • Explore and implement emerging technologies like robotics, advanced automation, or novel fabrication methods.
  • Regulatory & Environment Compliance: Ensure all designs meet rigorous technical, performance, and regulatory standards.
  • Advanced Modeling & Simulation: Utilize advanced simulation tools (such as FEA, CFD, and multi-body dynamics) to predict system behavior under operational conditions, design for failure modes, and optimize complex mechanical parts and assemblies.
  • End-to-End Project Ownership: Take full ownership of critical mechanical design projects from initial concept, prototyping, and testing through to manufacturing and final deployment. Develop comprehensive project plans, managing timelines and deliverables.
  • Design for Manufacturability (DFM): Work closely with NPI, Manufacturing, and Service teams to optimize designs for scalability and reliability. Perform DFMEAs and identify, research, and collaborate with strategic external vendors and suppliers.
  • Process Improvement: Propose and implement new engineering tools, testing methodologies, or design workflows to optimize team efficiency, reduce cycle times, and cut development costs without sacrificing quality.
  • Cross-Functional Team Leadership: Lead and influence cross-functional teams (including Chemistry, Molecular Biology, Software, and Electrical Engineering) to ensure seamless system integration.

Requirements

  • System Integration: Proven experience managing complex electromechanical assemblies containing motors, actuators, pumps, valves, regulators, sensors, cameras, and temperature controllers.
  • Demonstrated experience in at least two of the following specialized areas: control systems, dynamics/kinematics, mass flow/thermodynamics, optical systems, or fluidic handling.
  • Hands-on experience with machining, prototyping, and operating machine shop equipment.

Nice to have

  • High proficiency in 3D CAD design and surfacing ( SolidWorks and EPDM/PDMWorks preferred ).
  • Advanced expertise in Finite Element Analysis (FEA) and tolerance analysis.
  • Exceptional written and verbal communication skills, with a proven ability to distill complex technical data for executive-level presentations.
  • CAD & Simulation Proficiency: High proficiency in 3D CAD design and surfacing ( SolidWorks and EPDM/PDMWorks preferred ).
  • Preferred Skills and Experience

Skills

  • Project Execution & Process Optimization
  • Collaboration, Communication & Leadership

Compensation

  • $179,300 - $242,500 USD
  • About 10x Genomics
  • At 10x Genomics, accelerating our understanding of biology is more than a mission for us. It is a commitment. This is the century of biology, and the breakthroughs we make now have the potential to change the world.
  • We enable scientists to advance their research, allowing them to address scientific questions they did not even know they could ask. Our tools have enabled fundamental discoveries across biology including cancer, immunology, and neuroscience.
  • Our teams are empowered and encouraged to follow their passions, pursue new ideas, and perform at their best in an inclusive and dynamic environment.
  • We know that behind every scientific breakthrough, there is a deep infrastructure of talented people driving the life sciences industry and making it possible for scientists and clinicians to make new strides.

Benefits

  • Fueled by equal parts scientific vision and determined passion, we are delivering unprecedented innovation to short-read sequencing technologies and transforming how genomic information is accessed.

Company info

  • There's a dynamic energy here, and we're looking for the best of the best to be a part of it.
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This listing is sourced directly from 10x Genomics's careers page and normalized into a canonical job model.