Dyne Therapeutics

Dyne Therapeutics

Scientist, RNA Chemistry

Waltham, MA

Sponsorship not specified$118k-$145kDetected 21 days ago
ResearchMass SpectrometryAnimal StudiesCollaboration

About the role

  • Dyne Therapeutics is focused on delivering functional improvement for people living with genetically driven neuromuscular diseases.
  • The company is advancing clinical programs for Duchenne muscular dystrophy (DMD) and myotonic dystrophy type 1 (DM1) as well as a preclinical programs for facioscapulohumeral muscular dystrophy (FSHD) and Pompe disease.
  • Learn more at https://www.dyne-tx.com/, and follow us on X, LinkedIn and Facebook.

Requirements

  • Familiarity with biochemical and analytical assays used to assess stability,, and mechanism of action of modified RNA oligonucleotides.

Nice to have

  • PhD in Chemistry or a related scientific discipline with 2 years of e xperience, or MSc with a minimum of 8 years of relevant industry experience in biotechnology or life sciences.
  • Postdoctoral experience is a plus
  • Experience with oligonucleotide conjugation, including antibody conjugation, is a plus.

Skills

  • Interpretation of analytical data (HPLC, LCMS) to enable improved purity and yields of synthesized oligonucleotides.
  • Register synthesized oligonucleotides in the database (sequence, lot, and QC) and precisely report experiments in the ELN.
  • Generate intermediates to prepare antibody-oligonucleotide conjugates.
  • Cross-functional collaboration to define deliverables and timelines.

Compensation

  • $118,000 - $145,000 USD

Company info

  • We are developing therapeutics that target muscle and the central nervous system (CNS) to address the root cause of disease.
  • At Dyne, we are on a mission to deliver functional improvement for individuals, families and communities.

This listing is sourced directly from Dyne Therapeutics's careers page and normalized into a canonical job model.