Twenty Twenty Therapeutics

Twenty Twenty Therapeutics

Staff / Principal Frontend Software Engineer

Arlington, VA · Principal · Full-time

Sponsorship not specifiedDetected 284 days ago
JavaScriptTypeScriptReactHTMLCSSReduxCode ReviewGitMachine LearningData VisualizationCybersecurityDesign SystemsAccessibilityCypressPlaywrightTest AutomationCollaborationMentoring

About the role

  • ABOUT THE COMPANY America is under sustained cyber attack.
  • Our adversaries infiltrate our networks, steal our IP, and degrade the digital infrastructure that modern life runs on.
  • They've learned-correctly-that those attacks rarely produce consequences.

Responsibilities

  • Architect and build sophisticated React/TypeScript applications that operate smoothly at scale.
  • Design real-time UI experiences for complex cyber operation data, optimizing for speed and clarity.
  • Lead frontend technical architecture and design decisions.
  • Build and evolve interactive visualization systems (e.g., graphs, timelines, streaming views).
  • Coordinate execution across design, product, backend, and operations to deliver end-to-end features.
  • Troubleshoot production issues, lead frontend performance investigations, and improve reliability over time.

Requirements

  • You enjoy turning complex data into intuitive workflows that help users make decisions quickly.
  • You have 8+ years of professional frontend software development experience.
  • You have strong command of modern web fundamentals (JavaScript/TypeScript, HTML, CSS).
  • You have led frontend technical initiatives and mentored engineers through delivery and growth.
  • You have experience with automated testing practices and frameworks (e.g., Vitest, React Testing Library, Playwright or Cypress for E2E).
  • You have hands-on experience with state management patterns and libraries (e.g., Redux, Zustand, or React Query).
  • You have strong command of Git in a professional engineering environment, including branch workflows, code review practices, and CI integration.
  • You have a Bachelor's degree in CS/Engineering (or equivalent practical experience).
  • You have deep expertise building production React.js applications with TypeScript.
  • You have experience building for performance at scale (profiling, optimization, rendering strategies).
  • You have strong collaboration skills with product and design to deliver excellent UX.

Nice to have

  • You have experience with complex data visualization (e.g., D3.js, Chart.js, or similar).
  • You have worked with graph databases and understand graph query patterns (e.g., Neo4j).
  • You have experience with real-time streaming data and production visualization of live systems.
  • You have experience in defense, security, or other mission-critical domains.
  • You have built UI experiences that surface AI/ML outputs in operational workflows.
  • You have experience with component library or design system development (e.g., Storybook).

Benefits

  • Medical, dental, and vision plan options.
  • Life / AD&D, disability coverage options.
  • Paid parental leave for eligible full-time employees.
  • Paid holidays and flexible PTO.
  • HSA/FSA options, dependent care FSA.
  • Commuter benefits.
  • Building fitness center.
  • Desk setup stipend.
  • We consider all qualified applicants without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, age, veteran status, disability, or any other protected status.
  • Benefits vary by location, role, and eligibility.

Company info

  • America is under sustained cyber attack.
  • Twenty was founded to change that, by making our adversaries think twice before they attack us.
  • Our vision is American and allied primacy in cyberspace-a future where they cannot contest us, deterrence is assured, and the free world remains secure.
  • Founded in 2024, Twenty Technologies (www.twenty.io http://www.twenty.io) industrializes offensive cyber operations for the U.S. and its allies.
  • Headquartered in Arlington, Virginia, Twenty has raised $138M from Accel, Caffeinated Capital, Friends & Family Capital, Point72 Ventures, General Catalyst, and In-Q-Tel.
  • You'll own the frontend architecture for mission-critical operator experiences-building high-performance interfaces that visualize complex cyber operation data in real time.
  • You'll lead technical direction for UI systems, set the bar for engineering quality, and mentor engineers to move faster with confidence.
  • You'll partner closely with backend, product, design, and operational stakeholders to ship capabilities that must work reliably in both cloud and on-premises environments.
  • You'll be embedded in a cross-functional team building capabilities that go directly into operational use - small team, tight feedback loops, real consequences.

Equal opportunity

  • equal opportunity employer.
  • If you need a reasonable accommodation during the hiring process, let us know and we will work with you.

Visa & Work Authorization

  • Government security clearance
Apply directly at Twenty Twenty Therapeutics →Create a free account for alerts like thisView Twenty Twenty Therapeutics immigration profile

This listing is sourced directly from Twenty Twenty Therapeutics's careers page and normalized into a canonical job model.