Prime Medicine
Scientist II, Discovery & Platform Innovation
Cambridge, MA · Mid · Internship
Sponsorship not specified$131k-$146kDetected 9 hours ago
Machine LearningIntellectual PropertyBioinformaticsCRISPRMolecular BiologyCell CultureResearchAnimal StudiesAnimal ModelsCommunicationProblem SolvingPublic Speaking
About the role
- Communicate research findings clearly to internal scientific audiences; contribute to publications, patent filings, and conference presentations that advance Prime Medicine's scientific profile
Responsibilities
- Design and execute well-controlled experiments to probe structure-function relationships in Prime Editing system components; generate clean, interpretable data that drives platform design decisions
- Partner with cross-functional teams (Computational Biology, Technical Development, and program teams) as well as external collaborators and CROs to translate platform advances into program-specific solutions, including supporting Development Candidate nominations
- Maintain active engagement with the scientific literature and emerging technologies in genome editing, protein engineering, and therapeutic targets to anticipate the next wave of innovation and identify external advances or collaborations worth pursuing
- Design, construct, and systematically optimize Prime Editing approaches for new editing targets, first using in vitro cell culture systems and subsequently transitioning to in vivo development.
- Adhere to all laboratory safety requirements and procedures; author, review, and maintain accurate laboratory notebooks
Nice to have
- Ph.D. in Molecular Biology, Biochemistry, RNA Biology, Chemical Biology, or a closely related field
- preferred additional 2+ years of relevant postdoctoral and/or drug discovery research experience
- Experience working in a collaborative, cross-functional research environment with the ability to contribute meaningfully to team science while driving individual workstreams autonomously
- Experience translating genetic medicines therapeutic technologies from in vitro systems into in vivo animal models, using non-viral (e.g., LNP) or viral (e.g., AAV) delivery systems
- Working knowledge of human biology and animal models of disease as they relate to therapeutic development
- Excellent scientific communication skills, with the ability to present complex findings clearly to diverse audiences and contribute to written scientific outputs
- strong publication and presentation record, with engagement in the broader scientific community (e.g., conferences, scientific societies)
- Experience providing day-to-day scientific direction to research associates, interns, or co-op students, and comfort collaborating with and directing the work of external CROs
Compensation
- $131,000 - $146,000 USD
Equal opportunity
- Prime Medicine is proud to be an equal opportunity employer.
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This listing is sourced directly from Prime Medicine's careers page and normalized into a canonical job model.